Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset
Background To evaluate the prognostic effect of endovascular treatment (EVT) in patients with acute base artery occlusion (ABAO) within 24 h of onset, and analyze the factors related to prognosis.Methods A retrospective analysis was conducted on all ABAO patients who received EVT within 24 h of onse...
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Taylor & Francis Group
2025-12-01
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| Series: | Journal of Investigative Surgery |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/08941939.2024.2442382 |
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| author | Changchun Jiang Yu Fan Yuechun Li Wei Ma |
| author_facet | Changchun Jiang Yu Fan Yuechun Li Wei Ma |
| author_sort | Changchun Jiang |
| collection | DOAJ |
| description | Background To evaluate the prognostic effect of endovascular treatment (EVT) in patients with acute base artery occlusion (ABAO) within 24 h of onset, and analyze the factors related to prognosis.Methods A retrospective analysis was conducted on all ABAO patients who received EVT within 24 h of onset in the neurology department of Baotou Central Hospital in Inner Mongolia from May 2016 to October 2022. Good prognosis was defined as a Modified Rankin Scale (mRS) score of 0–3 and poor prognosis mRS score of 4–6 at 90 day follow-up, and factors related to prognosis were analyzed.Results Among the 77 patients included in the analysis, 68 patients (88.3%) achieved recanalization (modified thrombolysis in cerebral infarction, mTICI 2b/3 grade). Thirty eight patients (49.4%) achieved an overall good prognosis. In univariate analysis, age, baseline Glasgow Coma Scale (GCS), baseline National Institutes of Health Stroke Scale (NIHSS), posterior circulation Acute Stroke Prognostic Early CT score (pc ASPECTS), preoperative intravenous thrombolysis, and mTICI2b-3 were factors affecting good prognosis. Multivariate analysis showed that shorter onset to puncture time (OR 0.069; 95% CI, 0.009–0.519; p = 0.009), lower NIHSS (OR 1.179; 95% CI, 1.019–1.364; p = 0.027), and higher pc ASPECTS (OR 0.489, 95% CI, 0.250–0.959, p = 0.037) were factors influencing good prognosis in this study.Conclusions In summary, endovascular treatment for patients with acute basilar artery occlusion is safe and effective, but EVT may achieve better prognosis within 6 h of onset. The shorter time from onset to puncture at admission, lower baseline NIHSS score, and higher baseline pc-ASPECTS are factors affecting the good prognosis of patients at 90 days. |
| format | Article |
| id | doaj-art-da3daafd13a04de1bfb32cecdcb87518 |
| institution | Kabale University |
| issn | 0894-1939 1521-0553 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj-art-da3daafd13a04de1bfb32cecdcb875182025-01-06T00:01:14ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532025-12-0138110.1080/08941939.2024.2442382Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of OnsetChangchun Jiang0Yu Fan1Yuechun Li2Wei Ma3Department of Neurology, Baotou Central Hospital, Baotou, ChinaDepartment of Neurology, Baotou Central Hospital, Baotou, ChinaDepartment of Neurology, Baotou Central Hospital, Baotou, ChinaDepartment of Neurology, Baotou Central Hospital, Baotou, ChinaBackground To evaluate the prognostic effect of endovascular treatment (EVT) in patients with acute base artery occlusion (ABAO) within 24 h of onset, and analyze the factors related to prognosis.Methods A retrospective analysis was conducted on all ABAO patients who received EVT within 24 h of onset in the neurology department of Baotou Central Hospital in Inner Mongolia from May 2016 to October 2022. Good prognosis was defined as a Modified Rankin Scale (mRS) score of 0–3 and poor prognosis mRS score of 4–6 at 90 day follow-up, and factors related to prognosis were analyzed.Results Among the 77 patients included in the analysis, 68 patients (88.3%) achieved recanalization (modified thrombolysis in cerebral infarction, mTICI 2b/3 grade). Thirty eight patients (49.4%) achieved an overall good prognosis. In univariate analysis, age, baseline Glasgow Coma Scale (GCS), baseline National Institutes of Health Stroke Scale (NIHSS), posterior circulation Acute Stroke Prognostic Early CT score (pc ASPECTS), preoperative intravenous thrombolysis, and mTICI2b-3 were factors affecting good prognosis. Multivariate analysis showed that shorter onset to puncture time (OR 0.069; 95% CI, 0.009–0.519; p = 0.009), lower NIHSS (OR 1.179; 95% CI, 1.019–1.364; p = 0.027), and higher pc ASPECTS (OR 0.489, 95% CI, 0.250–0.959, p = 0.037) were factors influencing good prognosis in this study.Conclusions In summary, endovascular treatment for patients with acute basilar artery occlusion is safe and effective, but EVT may achieve better prognosis within 6 h of onset. The shorter time from onset to puncture at admission, lower baseline NIHSS score, and higher baseline pc-ASPECTS are factors affecting the good prognosis of patients at 90 days.https://www.tandfonline.com/doi/10.1080/08941939.2024.2442382Endovascular treatmentacute basilar artery occlusionprognosis |
| spellingShingle | Changchun Jiang Yu Fan Yuechun Li Wei Ma Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset Journal of Investigative Surgery Endovascular treatment acute basilar artery occlusion prognosis |
| title | Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset |
| title_full | Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset |
| title_fullStr | Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset |
| title_full_unstemmed | Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset |
| title_short | Study on the Prognostic Factors Related to Endovascular Treatment of Acute Basilar Artery Occlusion Within 24 Hours of Onset |
| title_sort | study on the prognostic factors related to endovascular treatment of acute basilar artery occlusion within 24 hours of onset |
| topic | Endovascular treatment acute basilar artery occlusion prognosis |
| url | https://www.tandfonline.com/doi/10.1080/08941939.2024.2442382 |
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