Pharmacodynamic characteristics and influencing factors of tapentadol for chronic pain relief under dose titration

Pharmacodynamic characteristics and influencing factors of tapentadol for chronic pain relief under dose titration

ObjectiveThe aim of this study was to establish a pharmacodynamic model of tapentadol analgesia under dose titration conditions, to quantitatively analyze the time-effect relationship of the drug, and to identify relevant influencing factors. This model is intended to provide a pharmacodynamic refer...

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Bibliographic Details
Main Authors: Liang Xin, Haoxiang Zhu, Suping Niu, Xie Han, Hongxian Pang, Jiangfan Li, Ye Hu, Xuhong Wang, Lujin Li, Yi Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pain Research
Subjects:
chronic pain
opioids
tapentadol
model-based meta-analysis
pharmacodynamic
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2024.1474529/full
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