NOX4 serves as a pan-cancer prognostic biomarker and therapeutic target in tumorigenesis

NOX4 serves as a pan-cancer prognostic biomarker and therapeutic target in tumorigenesis

Abstract NADPH oxidase 4 (NOX4) is a key regulator of intracellular reactive oxygen species (ROS) and plays a critical role in tumorigenesis and cancer progression. It contributes to cancer cell transformation, proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT). To eluci...

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Bibliographic Details
Main Authors: Jiting Sun, Zhiyuan Gong, Lijie Zheng, Zhixian Ding, Lusheng Wang, Yu Tang, Shizhan Deng, Yonggan Dong, Heng Tang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
NADPH oxidase 4
Pan-cancer
Prognostic biomarkers
Online Access:https://doi.org/10.1038/s41598-025-09690-9
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