Nanotechnology in photodynamic therapy
Photodynamic therapy (PDT) is a minimally invasive treatment that employs a photosensitizer to destroy cancer cells. Its efficiency is determined by the activation light features, which include the photosensitizer molecule, light wavelength, tumour location, and microenvironment. PDT is becoming inc...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024001535 |
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| author | Shrikant B. Mali Sachinkumar Dattatray Dahivelkar Swapna Arunkumar Mahale |
| author_facet | Shrikant B. Mali Sachinkumar Dattatray Dahivelkar Swapna Arunkumar Mahale |
| author_sort | Shrikant B. Mali |
| collection | DOAJ |
| description | Photodynamic therapy (PDT) is a minimally invasive treatment that employs a photosensitizer to destroy cancer cells. Its efficiency is determined by the activation light features, which include the photosensitizer molecule, light wavelength, tumour location, and microenvironment. PDT is becoming increasingly popular in the clinic because to its low risk, good selectivity, non-conflicting nature, and repeatability. It entails photoactivating a particular photosensitizer in a tumour microenvironment, resulting in singlet oxygen and reactive oxygen species (ROS), which destroy the tumour. However, PDT's efficacy in deep-seated cancers is restricted because to insufficient PS buildup, a hypoxic core, and poor light penetration. |
| format | Article |
| id | doaj-art-d9e38a70d9174a14b7841fede2ec631f |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-d9e38a70d9174a14b7841fede2ec631f2025-01-09T06:15:45ZengElsevierOral Oncology Reports2772-90602024-06-0110100307Nanotechnology in photodynamic therapyShrikant B. Mali0Sachinkumar Dattatray Dahivelkar1Swapna Arunkumar Mahale2Corresponding author.; Department of Oral and Maxillofacial Surgery Mahatma Gandhi Vidya Mandir's Dental College and Hospital, Nashik, IndiaDepartment of Oral and Maxillofacial Surgery Mahatma Gandhi Vidya Mandir's Dental College and Hospital, Nashik, IndiaDepartment of Periodontology Mahatma Gandhi Vidya Mandir's Dental College and Hospital, Nashik, IndiaPhotodynamic therapy (PDT) is a minimally invasive treatment that employs a photosensitizer to destroy cancer cells. Its efficiency is determined by the activation light features, which include the photosensitizer molecule, light wavelength, tumour location, and microenvironment. PDT is becoming increasingly popular in the clinic because to its low risk, good selectivity, non-conflicting nature, and repeatability. It entails photoactivating a particular photosensitizer in a tumour microenvironment, resulting in singlet oxygen and reactive oxygen species (ROS), which destroy the tumour. However, PDT's efficacy in deep-seated cancers is restricted because to insufficient PS buildup, a hypoxic core, and poor light penetration.http://www.sciencedirect.com/science/article/pii/S2772906024001535NanotechnologyCancerMicelleLiposomePhotodynamic therapy |
| spellingShingle | Shrikant B. Mali Sachinkumar Dattatray Dahivelkar Swapna Arunkumar Mahale Nanotechnology in photodynamic therapy Oral Oncology Reports Nanotechnology Cancer Micelle Liposome Photodynamic therapy |
| title | Nanotechnology in photodynamic therapy |
| title_full | Nanotechnology in photodynamic therapy |
| title_fullStr | Nanotechnology in photodynamic therapy |
| title_full_unstemmed | Nanotechnology in photodynamic therapy |
| title_short | Nanotechnology in photodynamic therapy |
| title_sort | nanotechnology in photodynamic therapy |
| topic | Nanotechnology Cancer Micelle Liposome Photodynamic therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024001535 |
| work_keys_str_mv | AT shrikantbmali nanotechnologyinphotodynamictherapy AT sachinkumardattatraydahivelkar nanotechnologyinphotodynamictherapy AT swapnaarunkumarmahale nanotechnologyinphotodynamictherapy |