Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer

Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer

Introduction: The aromatase enzyme plays an important role in the progress of hormone-dependent breast cancer, especially in estrogen receptor-positive (ER+) breast cancers. In case of postmenopausal women, the aromatization of androstenedione to estrone in adipose tissue is the most important sourc...

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Main Authors: Snehal Aditya Arvindekar, Sanket Rathod, Prafulla Balkrishna Choudhari, Pradnya Kiran Mane, Aditya Umesh Arvindekar, Suraj Narayan Mali, Bapu Thorat
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-09-01
Series:BioImpacts
Subjects:
in silico studies
natural products
aromatase inhibitors
qsar
breast cancer
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-14-27783.pdf
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