Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure

Dermal substitutes are crucial in soft-tissue reconstruction, minimising donor-site morbidity. However, conventional protocols often involve multi-staged procedures. This case series explores the effectiveness of integrating dermal substitutes with skin grafting in a one-stage process for soft-tissu...

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Main Authors: Pradeoth Mukundan Korambayil, Prashanth Ambookan Varkey, Edwina Mary Babu, Vinoth Kumar Dilliraj
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Clinical and Scientific Research
Subjects:
Online Access:https://journals.lww.com/10.4103/jcsr.jcsr_189_23
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author Pradeoth Mukundan Korambayil
Prashanth Ambookan Varkey
Edwina Mary Babu
Vinoth Kumar Dilliraj
author_facet Pradeoth Mukundan Korambayil
Prashanth Ambookan Varkey
Edwina Mary Babu
Vinoth Kumar Dilliraj
author_sort Pradeoth Mukundan Korambayil
collection DOAJ
description Dermal substitutes are crucial in soft-tissue reconstruction, minimising donor-site morbidity. However, conventional protocols often involve multi-staged procedures. This case series explores the effectiveness of integrating dermal substitutes with skin grafting in a one-stage process for soft-tissue coverage, supplemented by hyperbaric oxygen (HBO) therapy. The study, conducted in the plastic surgery and burns department from June 2022 to December 2022, included 10 patients with soft-tissue defects. All underwent single-stage dermal substitute and skin grafting, accompanied by HBO therapy for soft-tissue reconstruction. Among the 10 patients, seven had soft-tissue defects in the leg region, comprising three with chronic ulcers, three with post-traumatic leg defects and one with a chronic ulcer due to peripheral vascular disease. Two patients had post-burn contracture release and reconstruction, while one presented with a soft-tissue defect following sternal wound dehiscence post-irradiation. All wounds healed successfully without complications, and all patients received six sessions of HBO therapy. The incorporation of HBO therapy as an adjunct proved beneficial in achieving successful single-stage reconstruction of soft-tissue defects using dermal substitutes and skin grafting.
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institution Kabale University
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language English
publishDate 2024-12-01
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spelling doaj-art-d9d4a27ec18f42f0839f364c2acd1bb02025-01-11T09:44:24ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572024-12-0113Suppl 1S11S1410.4103/jcsr.jcsr_189_23Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedurePradeoth Mukundan KorambayilPrashanth Ambookan VarkeyEdwina Mary BabuVinoth Kumar DillirajDermal substitutes are crucial in soft-tissue reconstruction, minimising donor-site morbidity. However, conventional protocols often involve multi-staged procedures. This case series explores the effectiveness of integrating dermal substitutes with skin grafting in a one-stage process for soft-tissue coverage, supplemented by hyperbaric oxygen (HBO) therapy. The study, conducted in the plastic surgery and burns department from June 2022 to December 2022, included 10 patients with soft-tissue defects. All underwent single-stage dermal substitute and skin grafting, accompanied by HBO therapy for soft-tissue reconstruction. Among the 10 patients, seven had soft-tissue defects in the leg region, comprising three with chronic ulcers, three with post-traumatic leg defects and one with a chronic ulcer due to peripheral vascular disease. Two patients had post-burn contracture release and reconstruction, while one presented with a soft-tissue defect following sternal wound dehiscence post-irradiation. All wounds healed successfully without complications, and all patients received six sessions of HBO therapy. The incorporation of HBO therapy as an adjunct proved beneficial in achieving successful single-stage reconstruction of soft-tissue defects using dermal substitutes and skin grafting.https://journals.lww.com/10.4103/jcsr.jcsr_189_23dermal substitutehyperbaric oxygen therapyskin graftingsoft-tissue defect
spellingShingle Pradeoth Mukundan Korambayil
Prashanth Ambookan Varkey
Edwina Mary Babu
Vinoth Kumar Dilliraj
Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
Journal of Clinical and Scientific Research
dermal substitute
hyperbaric oxygen therapy
skin grafting
soft-tissue defect
title Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
title_full Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
title_fullStr Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
title_full_unstemmed Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
title_short Hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single-staged procedure
title_sort hyperbaric oxygen therapy as an adjunct for effective integration of dermal substitute with skin grafting in a single staged procedure
topic dermal substitute
hyperbaric oxygen therapy
skin grafting
soft-tissue defect
url https://journals.lww.com/10.4103/jcsr.jcsr_189_23
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AT prashanthambookanvarkey hyperbaricoxygentherapyasanadjunctforeffectiveintegrationofdermalsubstitutewithskingraftinginasinglestagedprocedure
AT edwinamarybabu hyperbaricoxygentherapyasanadjunctforeffectiveintegrationofdermalsubstitutewithskingraftinginasinglestagedprocedure
AT vinothkumardilliraj hyperbaricoxygentherapyasanadjunctforeffectiveintegrationofdermalsubstitutewithskingraftinginasinglestagedprocedure