Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis
Abstract Objectives The literature lacks comprehensive evidence on the efficacy of advanced platelet rich fibrin(A-PRF) in treating gingival recession. Therefore, this systematic review and meta-analysis aimed to evaluate the effectiveness of A-PRF in the treatment of gingival recession. Materials a...
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BMC
2024-11-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-024-05115-7 |
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| author | Wafaa Saleh Marwa Abdelhaleem Samah Elmeadawy |
| author_facet | Wafaa Saleh Marwa Abdelhaleem Samah Elmeadawy |
| author_sort | Wafaa Saleh |
| collection | DOAJ |
| description | Abstract Objectives The literature lacks comprehensive evidence on the efficacy of advanced platelet rich fibrin(A-PRF) in treating gingival recession. Therefore, this systematic review and meta-analysis aimed to evaluate the effectiveness of A-PRF in the treatment of gingival recession. Materials and methods We adhered to the guidelines of PRISMA in searching the following databases: PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, and Scopus to include all the eligible studies according to the prespecified inclusion and exclusion criteria. We conducted our search up to February 28, 2024. We conducted a meta-analysis of the primary and secondary clinical outcomes to measure the changes from baseline to 6 months after surgery. Results Our review included 10 randomized clinical trials in which 146 participants with 457 recession defects were included. We found that combination of A-PRF with various surgical techniques, such as coronally advanced flap (CAF) connective tissue graft (CTG), VISTA, tunneling, and pinhole surgical technique, demonstrated promising outcomes but varied by comparison group. We observed that CTG with CAF showed a higher reduction in recession depth in comparison to A-PRF with CAF. This review indicated no statistical or clinical differences in recession width, width of keratinized gingiva, probing depth, and clinical attachment level between the study and control groups. Conclusions Due to the less invasive nature of A-PRF, it provides a better clinical option to improve the outcomes of treating gingival recession. However, more well-designed RCTs with standardized approaches are needed to confirm these results. |
| format | Article |
| id | doaj-art-d9c1bfdcfa2c41cb9fa33544a1c150f3 |
| institution | Kabale University |
| issn | 1472-6831 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj-art-d9c1bfdcfa2c41cb9fa33544a1c150f32024-11-24T12:45:35ZengBMCBMC Oral Health1472-68312024-11-0124111510.1186/s12903-024-05115-7Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysisWafaa Saleh0Marwa Abdelhaleem1Samah Elmeadawy2Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura UniversityOral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Horus UniversityOral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura UniversityAbstract Objectives The literature lacks comprehensive evidence on the efficacy of advanced platelet rich fibrin(A-PRF) in treating gingival recession. Therefore, this systematic review and meta-analysis aimed to evaluate the effectiveness of A-PRF in the treatment of gingival recession. Materials and methods We adhered to the guidelines of PRISMA in searching the following databases: PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, and Scopus to include all the eligible studies according to the prespecified inclusion and exclusion criteria. We conducted our search up to February 28, 2024. We conducted a meta-analysis of the primary and secondary clinical outcomes to measure the changes from baseline to 6 months after surgery. Results Our review included 10 randomized clinical trials in which 146 participants with 457 recession defects were included. We found that combination of A-PRF with various surgical techniques, such as coronally advanced flap (CAF) connective tissue graft (CTG), VISTA, tunneling, and pinhole surgical technique, demonstrated promising outcomes but varied by comparison group. We observed that CTG with CAF showed a higher reduction in recession depth in comparison to A-PRF with CAF. This review indicated no statistical or clinical differences in recession width, width of keratinized gingiva, probing depth, and clinical attachment level between the study and control groups. Conclusions Due to the less invasive nature of A-PRF, it provides a better clinical option to improve the outcomes of treating gingival recession. However, more well-designed RCTs with standardized approaches are needed to confirm these results.https://doi.org/10.1186/s12903-024-05115-7Advanced platelet rich fibrinGingival recessionTreatmentSystematic review |
| spellingShingle | Wafaa Saleh Marwa Abdelhaleem Samah Elmeadawy Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis BMC Oral Health Advanced platelet rich fibrin Gingival recession Treatment Systematic review |
| title | Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis |
| title_full | Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis |
| title_fullStr | Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis |
| title_full_unstemmed | Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis |
| title_short | Assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession: a systematic review and meta-analysis |
| title_sort | assessing the effectiveness of advanced platelet rich fibrin in treating gingival recession a systematic review and meta analysis |
| topic | Advanced platelet rich fibrin Gingival recession Treatment Systematic review |
| url | https://doi.org/10.1186/s12903-024-05115-7 |
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