POLYMORPHISMS IN THE CYP-450 GENE AND MALARIA: A GENOTYPIC AND PHENOTYPIC RELATIONSHIP WITH THERAPEUTIC FAILURE
Introduction: Therapeutic failure in patients with malaria can occur due to various factors and polymorphisms in enzymes of the Cytochrome P450 (CYP450) family, responsible for around 90% of the metabolization of chloroquine and primaquine, can generate individuals who are low, intermediate or fast...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-11-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867024006834 |
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