Agent-based modelling of the early stages of actin polymerisation required to drive endocytosis in Saccharomyces cerevisiae

Abstract Endocytosis is critical. Its complexity means that many aspects remain poorly understood. We have developed an agent-based model covering key components of actin filament generation in endocytosis in Saccharomyces cerevisiae. The model incorporates realistic values for rates, affinities, co...

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Bibliographic Details
Main Authors: Lewis P. Hancock, Ellen G. Allwood, John S. Palmer, Kathryn R. Ayscough, Mike P. Williamson
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14248-w
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