European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant
The machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-11-01
|
| Series: | Transplant International |
| Subjects: | |
| Online Access: | https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13112/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846160719547990016 |
|---|---|
| author | Cristiano Amarelli Irene Bello Clemens Aigner Marius Berman Massimo Boffini Stephen Clark Marita Dalvindt Julien de Wolf Stephan Ensminger David Gomez de Antonio Lucas Hoyos Lucrezia Palmieri Martin Schweiger Sandro Sponga Bettina Wiegmann Arne Neyrinck the ESOT Guidelines Taskforce |
| author_facet | Cristiano Amarelli Irene Bello Clemens Aigner Marius Berman Massimo Boffini Stephen Clark Marita Dalvindt Julien de Wolf Stephan Ensminger David Gomez de Antonio Lucas Hoyos Lucrezia Palmieri Martin Schweiger Sandro Sponga Bettina Wiegmann Arne Neyrinck the ESOT Guidelines Taskforce |
| author_sort | Cristiano Amarelli |
| collection | DOAJ |
| description | The machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer in the field. This technology field has reached a critical turning point, with a growing number of publications coming predominantly from a few leading institutions, but still need solid scientific evidence. Due to the increasing need to expand the donor pool, especially in Europe, where the donor age is steeply increased, a consensus has been established to address the growing need and knowledge of machine perfusion in cardiothoracic transplantation, targeting the unmet scientific need in this growing field but also, priorities for development, and regional differences in utilization rates and organizational issues. To address MP in CT, the European Society of Organ Transplantation (ESOT) convened a dedicated Working group comprised of experts in CT to review literature about MP to develop guidelines that were subsequently discussed and voted on during the Consensus Conference that took place in person in Prague during the TLJ 3.0 in November 2022. The findings and recommendations of the Cardiothoracic Working Group on MP are presented in this article. |
| format | Article |
| id | doaj-art-d9298245c370489ab67bd9fd9c35a59d |
| institution | Kabale University |
| issn | 1432-2277 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Transplant International |
| spelling | doaj-art-d9298245c370489ab67bd9fd9c35a59d2024-11-22T04:11:42ZengFrontiers Media S.A.Transplant International1432-22772024-11-013710.3389/ti.2024.1311213112European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic TransplantCristiano Amarelli0Irene Bello1Clemens Aigner2Marius Berman3Massimo Boffini4Stephen Clark5Marita Dalvindt6Julien de Wolf7Stephan Ensminger8David Gomez de Antonio9Lucas Hoyos10Lucrezia Palmieri11Martin Schweiger12Sandro Sponga13Bettina Wiegmann14Arne Neyrinck15the ESOT Guidelines TaskforceDepartment of Cardiac Surgery and Transplants, Monaldi, Azienda dei Colli, Naples, ItalyInstitut Clínic Respiratorio, Hospital Clinic of Barcelona, Barcelona, SpainDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, AustriaTransplant Unit, Royal Papworth Hospital, NHS Foundation Trust, Cambridge, United KingdomCardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, ItalyDepartment Cardiothoracic Transplant, Newcastle University, Newcastle upon Tyne, United KingdomDepartment of Cardiothoracic Surgery, Lund University, Lund, SwedenDepartment of Thoracic Surgery, Lung Heart Institute, University Hospital of Lille, Lille, FranceDepartment of Cardiac and Thoracic Vascular Surgery, University Heart Center Lübeck, Lübeck, Germany0Department of Thoracic Surgery, Puerta de Hierro University Hospital Majadahonda, Madrid, Spain1Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland2Department of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli“, Naples, Italy3Department of Congenital Cardiovascular Surgery, Pediatric Heart Center, University Children’s Hospital Zurich, Zurich, Switzerland4Division of Cardiac Surgery, Cardiothoracic Department, University Hospital of Udine, Udine, Italy5Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hanover, Germany6Department of Cardiovascular Sciences, Anesthesiology and Algology, KU Leuven, Leuven, BelgiumThe machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer in the field. This technology field has reached a critical turning point, with a growing number of publications coming predominantly from a few leading institutions, but still need solid scientific evidence. Due to the increasing need to expand the donor pool, especially in Europe, where the donor age is steeply increased, a consensus has been established to address the growing need and knowledge of machine perfusion in cardiothoracic transplantation, targeting the unmet scientific need in this growing field but also, priorities for development, and regional differences in utilization rates and organizational issues. To address MP in CT, the European Society of Organ Transplantation (ESOT) convened a dedicated Working group comprised of experts in CT to review literature about MP to develop guidelines that were subsequently discussed and voted on during the Consensus Conference that took place in person in Prague during the TLJ 3.0 in November 2022. The findings and recommendations of the Cardiothoracic Working Group on MP are presented in this article.https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13112/fullmachine perfusionex-situ heart perfusionex-situ lung perfusiongraft preservationcardio-thoracic transplantation |
| spellingShingle | Cristiano Amarelli Irene Bello Clemens Aigner Marius Berman Massimo Boffini Stephen Clark Marita Dalvindt Julien de Wolf Stephan Ensminger David Gomez de Antonio Lucas Hoyos Lucrezia Palmieri Martin Schweiger Sandro Sponga Bettina Wiegmann Arne Neyrinck the ESOT Guidelines Taskforce European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant Transplant International machine perfusion ex-situ heart perfusion ex-situ lung perfusion graft preservation cardio-thoracic transplantation |
| title | European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant |
| title_full | European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant |
| title_fullStr | European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant |
| title_full_unstemmed | European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant |
| title_short | European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant |
| title_sort | european society of organ transplantation esot consensus statement on machine perfusion in cardiothoracic transplant |
| topic | machine perfusion ex-situ heart perfusion ex-situ lung perfusion graft preservation cardio-thoracic transplantation |
| url | https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13112/full |
| work_keys_str_mv | AT cristianoamarelli europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT irenebello europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT clemensaigner europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT mariusberman europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT massimoboffini europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT stephenclark europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT maritadalvindt europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT juliendewolf europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT stephanensminger europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT davidgomezdeantonio europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT lucashoyos europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT lucreziapalmieri europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT martinschweiger europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT sandrosponga europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT bettinawiegmann europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT arneneyrinck europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant AT theesotguidelinestaskforce europeansocietyoforgantransplantationesotconsensusstatementonmachineperfusionincardiothoracictransplant |