Neuronal activity inhibits mitochondrial transport only in synaptically connected segments of the axon

Due to their large scale and uniquely branched architecture, neurons critically rely on active transport of mitochondria in order to match energy production and calcium buffering to local demand. Consequently, defective mitochondrial trafficking is implicated in various neurological and neurodegener...

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Bibliographic Details
Main Authors: Tom Venneman, Pieter Vanden Berghe
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1509283/full
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