5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature
Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycl...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2011-03-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/317 |
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| _version_ | 1846143899341422592 |
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| author | Mariangela Greco Marianna Criscuolo Luana Fianchi Livio Pagano Maria Teresa Voso |
| author_facet | Mariangela Greco Marianna Criscuolo Luana Fianchi Livio Pagano Maria Teresa Voso |
| author_sort | Mariangela Greco |
| collection | DOAJ |
| description | Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start. |
| format | Article |
| id | doaj-art-d906f6ec08c244c9894cbca092a0b3e3 |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2011-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-d906f6ec08c244c9894cbca092a0b3e32024-12-02T09:52:13ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062011-03-0131e2011011e201101110.4084/mjhid.2011.0112095-Azacytidine in chronic myelomonocytic leukemia: case report and review of literatureMariangela GrecoMarianna CriscuoloLuana FianchiLivio PaganoMaria Teresa VosoHypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start.http://www.mjhid.org/index.php/mjhid/article/view/317CMML, 5-azacytidine |
| spellingShingle | Mariangela Greco Marianna Criscuolo Luana Fianchi Livio Pagano Maria Teresa Voso 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature Mediterranean Journal of Hematology and Infectious Diseases CMML, 5-azacytidine |
| title | 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature |
| title_full | 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature |
| title_fullStr | 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature |
| title_full_unstemmed | 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature |
| title_short | 5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature |
| title_sort | 5 azacytidine in chronic myelomonocytic leukemia case report and review of literature |
| topic | CMML, 5-azacytidine |
| url | http://www.mjhid.org/index.php/mjhid/article/view/317 |
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