Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review

[Objective:] To investigate the clinicopathological features, diagnosis and treatment of extranodal NK/T-cell lymphoma of nasal type (ENKTL-NT), and to provide reference for the diagnosis and treatment of clinicians. [Methods:] A case of palatal mucosa with a midline symmetry ulcer was followed up a...

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Main Authors: YU Donglin, CAO Zhang, WANG Wenlong, MA Xiangrui, TANG Juan, ZUO Jinhua
Format: Article
Language:zho
Published: Editorial Office of Journal of Oral and Maxillofacial Surgery 2025-04-01
Series:Kouqiang hemian waike zazhi
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Online Access:https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2025.02.013
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author YU Donglin
CAO Zhang
WANG Wenlong
MA Xiangrui
TANG Juan
ZUO Jinhua
author_facet YU Donglin
CAO Zhang
WANG Wenlong
MA Xiangrui
TANG Juan
ZUO Jinhua
author_sort YU Donglin
collection DOAJ
description [Objective:] To investigate the clinicopathological features, diagnosis and treatment of extranodal NK/T-cell lymphoma of nasal type (ENKTL-NT), and to provide reference for the diagnosis and treatment of clinicians. [Methods:] A case of palatal mucosa with a midline symmetry ulcer was followed up and ENKTL-NT was discussed, and analyzed in combination with literature. [Results:] After multiple biopsies were taken and the diagnosis was confirmed, the patient's condition was obviously improved by combined treatment. During nine months of postoperative follow-up, the patient died. [Conclusion:] ENKTL-NT is rare for stomatologists, and its clinical features are complex. Biopsy is often difficult to confirm the diagnosis. It is necessary to implement repeated multi-site biopsy strategies to improve diagnostic accuracy.
format Article
id doaj-art-d8f4916234b94c46acf27e779f089ddb
institution Kabale University
issn 1005-4979
language zho
publishDate 2025-04-01
publisher Editorial Office of Journal of Oral and Maxillofacial Surgery
record_format Article
series Kouqiang hemian waike zazhi
spelling doaj-art-d8f4916234b94c46acf27e779f089ddb2025-08-25T06:12:07ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792025-04-0135215715910.12439/kqhm.1005-4979.2025.02.013Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature reviewYU Donglin0CAO Zhang1WANG Wenlong2MA Xiangrui3TANG Juan4ZUO Jinhua5Department of Oral and Maxillofacial Surgery, Binzhou 256600Department of Pathology, Binzhou Medical University Hospital, Binzhou 256600Department of Oral and Maxillofacial Surgery, Binzhou 256600Department of Oral and Maxillofacial Surgery, Binzhou 256600Binzhou Medical University, Binzhou 256603, ChinaDepartment of Oral and Maxillofacial Surgery, Binzhou 256600[Objective:] To investigate the clinicopathological features, diagnosis and treatment of extranodal NK/T-cell lymphoma of nasal type (ENKTL-NT), and to provide reference for the diagnosis and treatment of clinicians. [Methods:] A case of palatal mucosa with a midline symmetry ulcer was followed up and ENKTL-NT was discussed, and analyzed in combination with literature. [Results:] After multiple biopsies were taken and the diagnosis was confirmed, the patient's condition was obviously improved by combined treatment. During nine months of postoperative follow-up, the patient died. [Conclusion:] ENKTL-NT is rare for stomatologists, and its clinical features are complex. Biopsy is often difficult to confirm the diagnosis. It is necessary to implement repeated multi-site biopsy strategies to improve diagnostic accuracy.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2025.02.013extranodal nk/t-cell lymphoma of nasal typeoral ulcerdiagnosis and treatment
spellingShingle YU Donglin
CAO Zhang
WANG Wenlong
MA Xiangrui
TANG Juan
ZUO Jinhua
Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
Kouqiang hemian waike zazhi
extranodal nk/t-cell lymphoma of nasal type
oral ulcer
diagnosis and treatment
title Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
title_full Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
title_fullStr Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
title_full_unstemmed Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
title_short Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review
title_sort extranodal nk t cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom a case report and literature review
topic extranodal nk/t-cell lymphoma of nasal type
oral ulcer
diagnosis and treatment
url https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2025.02.013
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AT wangwenlong extranodalnktcelllymphomaofnasaltypewithmidlinesymmetryoralulcerasthemainsymptomacasereportandliteraturereview
AT maxiangrui extranodalnktcelllymphomaofnasaltypewithmidlinesymmetryoralulcerasthemainsymptomacasereportandliteraturereview
AT tangjuan extranodalnktcelllymphomaofnasaltypewithmidlinesymmetryoralulcerasthemainsymptomacasereportandliteraturereview
AT zuojinhua extranodalnktcelllymphomaofnasaltypewithmidlinesymmetryoralulcerasthemainsymptomacasereportandliteraturereview