Nanoparticle ultrasonication: a promising approach for reducing bacterial biofilm in total joint infection—an in vivo rat model investigation

Nanoparticle ultrasonication: a promising approach for reducing bacterial biofilm in total joint infection—an in vivo rat model investigation

Abstract Background While the benefits of sonication for improving periprosthetic joint infection (PJI) are well-documented, its potential therapeutic effect against bacterial biofilm remains unstudied. This study aimed to investigate the safety and efficacy of a novel nanoparticle ultrasonication p...

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Bibliographic Details
Main Authors: Itay Ashkenazi, Mark Longwell, Barbara Byers, Rachael Kreft, Roi Ramot, Muhammad A. Haider, Yair Ramot, Ran Schwarzkopf
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Arthroplasty
Subjects:
Periprosthetic joint infection (PJI)
Ultrasonication
Biofilm
Animal model
DAIR
Online Access:https://doi.org/10.1186/s42836-024-00279-7
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https://doi.org/10.1186/s42836-024-00279-7

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