Association of Delayed Denosumab Dosing with Increased Risk of Fractures: A Population-Based Retrospective Study

Association of Delayed Denosumab Dosing with Increased Risk of Fractures: A Population-Based Retrospective Study

Background Inhibitory effects of denosumab on bone remodeling are reversible and disappear once treatment is discontinued. Herein, we examined whether and to what extent delayed denosumab administration is also associated with fracture risk using nation-wide data. Methods The study cohort included w...

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Bibliographic Details
Main Authors: Kyoung Min Kim, Seol A Jang, Nam Ki Hong, Chul Sik Kim, Yumie Rhee, Seok Won Park, Steven R. Cummings, Gi Hyeon Seo
Format: Article
Language:English
Published: Korean Endocrine Society 2024-12-01
Series:Endocrinology and Metabolism
Subjects:
denosumab
fractures
osteoporosis
discontinuation
Online Access:http://www.e-enm.org/upload/pdf/enm-2024-2047.pdf
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