The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults
Abstract Novel anthropometric indices are more closely related to metabolic abnormalities than traditional anthropometric indices. Fewer studies have been conducted based on the relationship between novel anthropometric indicators and hyperuricemia. This study was to analyze the serum uric acid (SUA...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-024-84617-4 |
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| author | Li Hongwei Shen Zhenhai Jiang Wei Jia Bing Li Shaolei Zhang Ping Wang Liuyu Yuan Peng Lu Yun |
| author_facet | Li Hongwei Shen Zhenhai Jiang Wei Jia Bing Li Shaolei Zhang Ping Wang Liuyu Yuan Peng Lu Yun |
| author_sort | Li Hongwei |
| collection | DOAJ |
| description | Abstract Novel anthropometric indices are more closely related to metabolic abnormalities than traditional anthropometric indices. Fewer studies have been conducted based on the relationship between novel anthropometric indicators and hyperuricemia. This study was to analyze the serum uric acid (SUA) levels of adults and the relationship between hyperuricemia and these new indicators in Su-Wuxi-Chang area of China, in order to provide a theoretical basis for the management of SUA levels in patients with hyperuricemia. A total of 14,834 adults were enrolled. The information of height, weight, waist circumference, lifestyle, fasting plasma glucose (FPG), lipids, and SUA were collected. The traditional obesity indices and novel anthropometric indices were calculated by formulas. Lipid accumulation product (LAP), triglyceride glucose (TyG) and body roundness index (BRI) are independent risk factors for hyperuricemia in both men and women (P < 0.001). In males, the predictive ability of LAP and TyG to the incidence of hyperuricemia were 0.694 and 0.661 in AUC area, respectively (P < 0.001) and which were 0.767 and 0.746 respectively in females (P < 0.001). In both men and women, the LAP and TyG indices were more predictive of hyperuricemia than the other indices (P < 0.001). The capacity of LAP and TyG indexes were better than other traditional anthropometric indexes in predicting hyperuricemia in this population. The predicted hyperuricemia ablity of LAP in both male and female better than other traditional and new anthropometric indicators. |
| format | Article |
| id | doaj-art-d8af8bf02ad8428dadf992899bcb0802 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-d8af8bf02ad8428dadf992899bcb08022025-01-12T12:18:23ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-024-84617-4The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adultsLi Hongwei0Shen Zhenhai1Jiang Wei2Jia Bing3Li Shaolei4Zhang Ping5Wang Liuyu6Yuan Peng7Lu Yun8Wuxi People’s Hospital, Wuxi Medical Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Nanjing Medical UniversityDepartment of Cardiovascular Medicine, Jiangsu Provincial People’s Hospital Group Taihu Sanatorium of Jiangsu ProvinceDepartment of Rehabilitation, Jiangsu Rongjun HospitalDepartment of Endocrine, Affiliated Hospital of Jiangsu Institute of Nuclear MedicineDepartment of Cardiovascular Medicine, Jiangsu Provincial People’s Hospital Group Taihu Sanatorium of Jiangsu ProvinceDepartment of Cardiovascular Medicine, Jiangsu Provincial People’s Hospital Group Taihu Sanatorium of Jiangsu ProvinceDepartment of Cardiovascular Medicine, Jiangsu Provincial People’s Hospital Group Taihu Sanatorium of Jiangsu ProvinceWuxi People’s Hospital, Wuxi Medical Center, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Nanjing Medical UniversityDepartment of Cardiovascular Medicine, Jiangsu Provincial People’s Hospital Group Taihu Sanatorium of Jiangsu ProvinceAbstract Novel anthropometric indices are more closely related to metabolic abnormalities than traditional anthropometric indices. Fewer studies have been conducted based on the relationship between novel anthropometric indicators and hyperuricemia. This study was to analyze the serum uric acid (SUA) levels of adults and the relationship between hyperuricemia and these new indicators in Su-Wuxi-Chang area of China, in order to provide a theoretical basis for the management of SUA levels in patients with hyperuricemia. A total of 14,834 adults were enrolled. The information of height, weight, waist circumference, lifestyle, fasting plasma glucose (FPG), lipids, and SUA were collected. The traditional obesity indices and novel anthropometric indices were calculated by formulas. Lipid accumulation product (LAP), triglyceride glucose (TyG) and body roundness index (BRI) are independent risk factors for hyperuricemia in both men and women (P < 0.001). In males, the predictive ability of LAP and TyG to the incidence of hyperuricemia were 0.694 and 0.661 in AUC area, respectively (P < 0.001) and which were 0.767 and 0.746 respectively in females (P < 0.001). In both men and women, the LAP and TyG indices were more predictive of hyperuricemia than the other indices (P < 0.001). The capacity of LAP and TyG indexes were better than other traditional anthropometric indexes in predicting hyperuricemia in this population. The predicted hyperuricemia ablity of LAP in both male and female better than other traditional and new anthropometric indicators.https://doi.org/10.1038/s41598-024-84617-4Novel anthropometric parametersHyperuricemiaObesity |
| spellingShingle | Li Hongwei Shen Zhenhai Jiang Wei Jia Bing Li Shaolei Zhang Ping Wang Liuyu Yuan Peng Lu Yun The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults Scientific Reports Novel anthropometric parameters Hyperuricemia Obesity |
| title | The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| title_full | The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| title_fullStr | The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| title_full_unstemmed | The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| title_short | The effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| title_sort | effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults |
| topic | Novel anthropometric parameters Hyperuricemia Obesity |
| url | https://doi.org/10.1038/s41598-024-84617-4 |
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