Stem extract from Costus afer (Bush cane) prevents ethanol-induced neuronal degeneration in mice via an antioxidant-inflammatory pathway

Stem extract from Costus afer (Bush cane) prevents ethanol-induced neuronal degeneration in mice via an antioxidant-inflammatory pathway

Background: Excessive alcohol consumption is associated with memory impairment and can lead to Alzheimer's disease-like dementia, contributing to the rising prevalence of dementia worldwide. Costus afer (Bush cane) is a medicinal plant widely used in traditional African medicine for its anti-in...

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Bibliographic Details
Main Authors: Agnes Igimi Odey, Sunday A. Bisong, Iliya Ezekiel, Ejike Daniel Eze, Solomon Emmanuel Nachamada, Ayomide Victor Atoki, Olufunke Onaadepo, Patrick Maduabuchi Aja
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Phytomedicine Plus
Subjects:
Ethanol
C. afer
Cortico-hippocampal and cerebellar neurons
Oxidative stress
Inflammatory stress
Spatial memory
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031324001271
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