Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients

Objective To investigate the risk factors for complications in breast cancer patients with totally implantable access ports (TIAPs). Methods This retrospective case-control study involved 471 breast cancer (BC) patients who received TIAPs during chemotherapy. We compared the demographic and clinical...

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Main Authors: Yangfan Fan MD, Xiaohang Ye MD, Fangfang Chen MD, Fang Wan MD, Dianlei Liu MD, Tao Zhang MD, PhD, Jingpei Long MD
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/10732748251336407
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author Yangfan Fan MD
Xiaohang Ye MD
Fangfang Chen MD
Fang Wan MD
Dianlei Liu MD
Tao Zhang MD, PhD
Jingpei Long MD
author_facet Yangfan Fan MD
Xiaohang Ye MD
Fangfang Chen MD
Fang Wan MD
Dianlei Liu MD
Tao Zhang MD, PhD
Jingpei Long MD
author_sort Yangfan Fan MD
collection DOAJ
description Objective To investigate the risk factors for complications in breast cancer patients with totally implantable access ports (TIAPs). Methods This retrospective case-control study involved 471 breast cancer (BC) patients who received TIAPs during chemotherapy. We compared the demographic and clinical characteristics of patients with complications to those without, analyzed independent risk factors using binary logistic regression, and identified differences in complication rates based on catheterization site. Results The most frequent complication was catheter malposition, followed by infection, thrombosis, hemothorax, and port rotation. Complications were more common in right-side BC cases ( P = .026) and with left-side insertions ( P = .012). Binary logistic regression identified independent risk factors for complications: catheter tip location (OR = 0.599, P = .013), and catheterization site (OR = 0.319, P = .019). Notably, left-side insertion significantly increased the risk of overall complications and catheter malposition compared to right-side insertion (OR = 3.534, P = .008; OR = 5.624, P = .004, respectively). Conclusion Catheter tip location and catheterization site independently affect complications and catheter malposition. For TIAPs implantation, particularly on the left side, a lower catheter tip location is advised to reduce complications and enhance safety.
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spelling doaj-art-d86d53df3aae4062a78873f8cc31cef62025-08-20T03:51:59ZengSAGE PublishingCancer Control1526-23592025-04-013210.1177/10732748251336407Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer PatientsYangfan Fan MDXiaohang Ye MDFangfang Chen MDFang Wan MDDianlei Liu MDTao Zhang MD, PhDJingpei Long MDObjective To investigate the risk factors for complications in breast cancer patients with totally implantable access ports (TIAPs). Methods This retrospective case-control study involved 471 breast cancer (BC) patients who received TIAPs during chemotherapy. We compared the demographic and clinical characteristics of patients with complications to those without, analyzed independent risk factors using binary logistic regression, and identified differences in complication rates based on catheterization site. Results The most frequent complication was catheter malposition, followed by infection, thrombosis, hemothorax, and port rotation. Complications were more common in right-side BC cases ( P = .026) and with left-side insertions ( P = .012). Binary logistic regression identified independent risk factors for complications: catheter tip location (OR = 0.599, P = .013), and catheterization site (OR = 0.319, P = .019). Notably, left-side insertion significantly increased the risk of overall complications and catheter malposition compared to right-side insertion (OR = 3.534, P = .008; OR = 5.624, P = .004, respectively). Conclusion Catheter tip location and catheterization site independently affect complications and catheter malposition. For TIAPs implantation, particularly on the left side, a lower catheter tip location is advised to reduce complications and enhance safety.https://doi.org/10.1177/10732748251336407
spellingShingle Yangfan Fan MD
Xiaohang Ye MD
Fangfang Chen MD
Fang Wan MD
Dianlei Liu MD
Tao Zhang MD, PhD
Jingpei Long MD
Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
Cancer Control
title Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
title_full Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
title_fullStr Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
title_full_unstemmed Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
title_short Risk Factors for Totally Implantable Access Ports Associated Complications in Breast Cancer Patients
title_sort risk factors for totally implantable access ports associated complications in breast cancer patients
url https://doi.org/10.1177/10732748251336407
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