Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review
IntroductionCerebral palsy (CP) is a group of permanent disorders of movement development that may cause activity limitations. In this context, robot-assisted therapy might play a key role in clinical management. This comprehensive systematic review aimed to investigate the efficacy of robotic syste...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1499249/full |
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| author | Daniela Cardone David Perpetuini Marta Di Nicola Arcangelo Merla Giovanni Morone Giovanni Morone Irene Ciancarelli Antimo Moretti Antimo Moretti Francesca Gimigliano Francesca Gimigliano Alice Cichelli Francesco De Flaviis Alex Martino Cinnera Teresa Paolucci |
| author_facet | Daniela Cardone David Perpetuini Marta Di Nicola Arcangelo Merla Giovanni Morone Giovanni Morone Irene Ciancarelli Antimo Moretti Antimo Moretti Francesca Gimigliano Francesca Gimigliano Alice Cichelli Francesco De Flaviis Alex Martino Cinnera Teresa Paolucci |
| author_sort | Daniela Cardone |
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| description | IntroductionCerebral palsy (CP) is a group of permanent disorders of movement development that may cause activity limitations. In this context, robot-assisted therapy might play a key role in clinical management. This comprehensive systematic review aimed to investigate the efficacy of robotic systems in improving upper limb (UL) functions in children with CP.MethodsPubMed, EMBASE, Scopus, and PEDro were searched from inception to February 2024. The risk of bias was assessed with the Joanna Briggs Institute critical appraisal tools battery.ResultsOf 756 articles identified, 14 studies involving 193 children with CP with a judged to be of good methodological quality, but with a lack in the study design, were included in the final synthesis. In the included studies a wide range of devices was used, both exoskeletons and end-effectors, both wearable and non-wearable. The CP children who underwent robot-assisted therapy reported a significant overall increase in clinical assessment, specifically in UL movements and manual dexterity. The clinical improvement was often accompanied by a gain also in instrumental assessments (i.e., kinematic analysis, EMG).DiscussionThe present review suggested that robot-assisted therapy can improve UL motor functions in children with CP. Moreover, the availability of different devices with adjustable parameters can represent an important resource in proposing patient-centered-personalized rehabilitation protocols to enhance the efficacy of rehabilitation and integration into daily life. However, the limited sample size and lack of standardized and clearly reproducible protocols impose to recommend the use of robot-assisted therapy as an integration to usual rehabilitation and not as a replacement.Systematic review registrationhttps://osf.io/a78zb/. |
| format | Article |
| id | doaj-art-d86ab502ea2d450ea279ec7ea1ead585 |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-d86ab502ea2d450ea279ec7ea1ead5852025-01-06T06:59:13ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011510.3389/fneur.2024.14992491499249Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic reviewDaniela Cardone0David Perpetuini1Marta Di Nicola2Arcangelo Merla3Giovanni Morone4Giovanni Morone5Irene Ciancarelli6Antimo Moretti7Antimo Moretti8Francesca Gimigliano9Francesca Gimigliano10Alice Cichelli11Francesco De Flaviis12Alex Martino Cinnera13Teresa Paolucci14Department of Engineering and Geology, University “G. d’Annunzio” of Chieti-Pescara, Pescara, ItalyDepartment of Engineering and Geology, University “G. d’Annunzio” of Chieti-Pescara, Pescara, ItalyDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University “G. d’Annunzio” of Chieti-Pescara, Chieti, ItalyDepartment of Engineering and Geology, University “G. d’Annunzio” of Chieti-Pescara, Pescara, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, ItalySan Raffaele Institute of Sulmona, Sulmona, ItalyDepartment of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, ItalyDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, ItalyMultidisciplinary Department of Medical and Surgical Specialties and Dentistry, University of Campania “Luigi Vanvitelli”, Naples, ItalyDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, ItalyDepartment of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, ItalyDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University “G. d’Annunzio” of Chieti-Pescara, Chieti, ItalyDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University “G. d’Annunzio” of Chieti-Pescara, Chieti, ItalyDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, ItalyDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University “G. d’Annunzio” of Chieti-Pescara, Chieti, ItalyIntroductionCerebral palsy (CP) is a group of permanent disorders of movement development that may cause activity limitations. In this context, robot-assisted therapy might play a key role in clinical management. This comprehensive systematic review aimed to investigate the efficacy of robotic systems in improving upper limb (UL) functions in children with CP.MethodsPubMed, EMBASE, Scopus, and PEDro were searched from inception to February 2024. The risk of bias was assessed with the Joanna Briggs Institute critical appraisal tools battery.ResultsOf 756 articles identified, 14 studies involving 193 children with CP with a judged to be of good methodological quality, but with a lack in the study design, were included in the final synthesis. In the included studies a wide range of devices was used, both exoskeletons and end-effectors, both wearable and non-wearable. The CP children who underwent robot-assisted therapy reported a significant overall increase in clinical assessment, specifically in UL movements and manual dexterity. The clinical improvement was often accompanied by a gain also in instrumental assessments (i.e., kinematic analysis, EMG).DiscussionThe present review suggested that robot-assisted therapy can improve UL motor functions in children with CP. Moreover, the availability of different devices with adjustable parameters can represent an important resource in proposing patient-centered-personalized rehabilitation protocols to enhance the efficacy of rehabilitation and integration into daily life. However, the limited sample size and lack of standardized and clearly reproducible protocols impose to recommend the use of robot-assisted therapy as an integration to usual rehabilitation and not as a replacement.Systematic review registrationhttps://osf.io/a78zb/.https://www.frontiersin.org/articles/10.3389/fneur.2024.1499249/fullrehabilitationroboticshemiplegiaupper extremitiesexoskeletonendeffector |
| spellingShingle | Daniela Cardone David Perpetuini Marta Di Nicola Arcangelo Merla Giovanni Morone Giovanni Morone Irene Ciancarelli Antimo Moretti Antimo Moretti Francesca Gimigliano Francesca Gimigliano Alice Cichelli Francesco De Flaviis Alex Martino Cinnera Teresa Paolucci Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review Frontiers in Neurology rehabilitation robotics hemiplegia upper extremities exoskeleton endeffector |
| title | Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review |
| title_full | Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review |
| title_fullStr | Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review |
| title_full_unstemmed | Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review |
| title_short | Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review |
| title_sort | robot assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy a systematic review |
| topic | rehabilitation robotics hemiplegia upper extremities exoskeleton endeffector |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1499249/full |
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