Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy
Ahmad A Imran,1 Jagmeet Singh Bajwa,2 Sibasis Daspal,1 Darryl J Adamko3 1Division of Neonatology, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 2Division of Research, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 3Divi...
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2024-12-01
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| author | Imran AA Bajwa JS Daspal S Adamko DJ |
| author_facet | Imran AA Bajwa JS Daspal S Adamko DJ |
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| description | Ahmad A Imran,1 Jagmeet Singh Bajwa,2 Sibasis Daspal,1 Darryl J Adamko3 1Division of Neonatology, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 2Division of Research, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 3Division of Respirology, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaCorrespondence: Darryl J Adamko, Department of Pediatrics, College of Medicine, 103 hospital Drive, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada, Tel +1 306 844-1275, Fax +1 306 844-1210, Email darryl.adamko@usask.caObjective: Near-infrared spectroscopy (NIRS) measures cerebral oxygenation and could measure the risk of hypoxia or hyperoxia in infants with bronchopulmonary dysplasia (BPD). We lack normalized data for NIRS values in neonates. We sought normative values of NIRS and proposed that NIRS could better identify a safe oxygen flow rate compared to pulse oximetry (POX).Methods: This prospective cohort study compared POX and NIRS values in healthy infants in room air (n = 22) with BPD infants (n = 10) on oxygen (0.03, 0.06, 0.12 L/min).Results: In healthy infants, the average POX value was 97.8%, and NIRS was 78.24%. Time (% time) with hypoxia was similarly low using either POX or NIRS (3.5% and 1.4%). On oxygen, % time with hypoxemia was similarly low with both POX or NIRS (0.03 lpm: 2.35% POX and 0.01% NIRS; 0.06 lpm: 1.43% POX and 0.6% NIRS; 0.12 lpm: 1.46% POX and 0.2% NIRS). In contrast, the potential hyperoxia %time was higher using POX compared to NIRS (96.5% vs 47.9%) in room air healthy infants. Similarly, hyperoxia %time was more common with POX compared to NIRS, but there was no difference with increasing oxygen flow rates (0.03 lpm, 82.13% POX and 41.5% NIRS; 0.06 lpm: 92.49% POX and 34.4% NIRS; 0.12 lpm: 87.00% POX and 34.8% NIRS).Conclusion: We did not see a dose response correlation between oxygen flow rate and time spent in the hyperoxemic range across different flow rates by POX or cerebral NIRS. We did not see a benefit of NIRS in setting home oxygen flow rates.Keywords: near infrared spectroscopy, hyperoxia, home oxygen |
| format | Article |
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| institution | Kabale University |
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| spelling | doaj-art-d82bfe8a632d48d5a486fdd9ce28050c2024-12-08T17:58:38ZengDove Medical PressResearch and Reports in Neonatology1179-99352024-12-01Volume 1410911598039Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared SpectroscopyImran AABajwa JSDaspal SAdamko DJAhmad A Imran,1 Jagmeet Singh Bajwa,2 Sibasis Daspal,1 Darryl J Adamko3 1Division of Neonatology, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 2Division of Research, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; 3Division of Respirology, Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaCorrespondence: Darryl J Adamko, Department of Pediatrics, College of Medicine, 103 hospital Drive, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada, Tel +1 306 844-1275, Fax +1 306 844-1210, Email darryl.adamko@usask.caObjective: Near-infrared spectroscopy (NIRS) measures cerebral oxygenation and could measure the risk of hypoxia or hyperoxia in infants with bronchopulmonary dysplasia (BPD). We lack normalized data for NIRS values in neonates. We sought normative values of NIRS and proposed that NIRS could better identify a safe oxygen flow rate compared to pulse oximetry (POX).Methods: This prospective cohort study compared POX and NIRS values in healthy infants in room air (n = 22) with BPD infants (n = 10) on oxygen (0.03, 0.06, 0.12 L/min).Results: In healthy infants, the average POX value was 97.8%, and NIRS was 78.24%. Time (% time) with hypoxia was similarly low using either POX or NIRS (3.5% and 1.4%). On oxygen, % time with hypoxemia was similarly low with both POX or NIRS (0.03 lpm: 2.35% POX and 0.01% NIRS; 0.06 lpm: 1.43% POX and 0.6% NIRS; 0.12 lpm: 1.46% POX and 0.2% NIRS). In contrast, the potential hyperoxia %time was higher using POX compared to NIRS (96.5% vs 47.9%) in room air healthy infants. Similarly, hyperoxia %time was more common with POX compared to NIRS, but there was no difference with increasing oxygen flow rates (0.03 lpm, 82.13% POX and 41.5% NIRS; 0.06 lpm: 92.49% POX and 34.4% NIRS; 0.12 lpm: 87.00% POX and 34.8% NIRS).Conclusion: We did not see a dose response correlation between oxygen flow rate and time spent in the hyperoxemic range across different flow rates by POX or cerebral NIRS. We did not see a benefit of NIRS in setting home oxygen flow rates.Keywords: near infrared spectroscopy, hyperoxia, home oxygenhttps://www.dovepress.com/determining-optimal-home-oxygen-flow-rate-for-infants-with-bronchopulm-peer-reviewed-fulltext-article-RRNnear infrared spectroscopyhyperoxiahome oxygen |
| spellingShingle | Imran AA Bajwa JS Daspal S Adamko DJ Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy Research and Reports in Neonatology near infrared spectroscopy hyperoxia home oxygen |
| title | Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy |
| title_full | Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy |
| title_fullStr | Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy |
| title_full_unstemmed | Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy |
| title_short | Determining Optimal Home Oxygen Flow Rate For Infants With Bronchopulmonary Dysplasia (BPD) Using Near Infrared Spectroscopy |
| title_sort | determining optimal home oxygen flow rate for infants with bronchopulmonary dysplasia bpd using near infrared spectroscopy |
| topic | near infrared spectroscopy hyperoxia home oxygen |
| url | https://www.dovepress.com/determining-optimal-home-oxygen-flow-rate-for-infants-with-bronchopulm-peer-reviewed-fulltext-article-RRN |
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