Integrated analysis of shared gene expression signatures and immune microenvironment heterogeneity in type 2 diabetes mellitus and colorectal cancer

Integrated analysis of shared gene expression signatures and immune microenvironment heterogeneity in type 2 diabetes mellitus and colorectal cancer

Abstract Emerging evidence suggests a bidirectional relationship between colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM), yet the shared molecular mechanisms and prognostic biomarkers remain poorly characterized. This study aimed to identify novel biomarkers linking CRC and T2DM pathogen...

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Bibliographic Details
Main Authors: Zhaohui Wu, Liuliu Cao, Jie Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Type 2 diabetes mellitus
Machine learning
Single-cell
Online Access:https://doi.org/10.1038/s41598-025-07015-4
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