Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study
ObjectiveWe aimed to identify the association between Health-related quality of life (HRQoL) and muscle strength in patients undergoing maintenance hemodialysis (MHD).MethodsIn this cross-sectional study from March 2021 to December 2021, 110 MHD patients with a mean age of 63.9 ± 13.0 years and a me...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2024.1478209/full |
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| author | Chunlei Li Chunlei Li Xiangyou Pan Shilin Xu Jianguang Hu Xiaoshi Zhong Luona Wen Jingxian Qiu Rongshao Tan Rongshao Tan |
| author_facet | Chunlei Li Chunlei Li Xiangyou Pan Shilin Xu Jianguang Hu Xiaoshi Zhong Luona Wen Jingxian Qiu Rongshao Tan Rongshao Tan |
| author_sort | Chunlei Li |
| collection | DOAJ |
| description | ObjectiveWe aimed to identify the association between Health-related quality of life (HRQoL) and muscle strength in patients undergoing maintenance hemodialysis (MHD).MethodsIn this cross-sectional study from March 2021 to December 2021, 110 MHD patients with a mean age of 63.9 ± 13.0 years and a median dialysis vintage of 25.5 (12.0–52.3) months, were enrolled at a hemodialysis center in Guangzhou city, China. HRQoL was assessed using the Short Form 36 Health Survey (SF-36) and converted into the Physical Component Summary (PCS) and the Mental Component Summary (MCS). The groups were assigned according to the mean score of PCS and MCS, and those with higher PCS/MCS scores (high-PCS/MCS) were compared with those with lower PCS/MCS scores (low-PCS/MCS). Independent factors were evaluated using multivariate analysis. Muscle strength was estimated by handgrip strength (HGS).ResultsThe mean HGS was 23.7 ± 9.60 kg in men and 14.3 ± 5.30 kg in women. Compared to the high-PCS group, the low-PCS group had older age, higher levels of creatinine, total cholesterol, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6), and had lower HGS (all p < 0.05). After adjusting for confounding factors in different models, the five-model multivariate binary logistic regression analyses revealed that HGS was the only independent factor in PCS domain, but not in MCS.ConclusionHGS may be an independent factor of poor HRQoL in MHD patients, particularly in relation to physical health. The management of muscle strength may improve the HRQoL in MHD patients.Clinical trial registrationThe study was registered at https://www.chictr.org.cn/ as ChiCTR2100053790. |
| format | Article |
| id | doaj-art-d7f0a4821e854cff86ec946c438458a0 |
| institution | Kabale University |
| issn | 2296-861X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-d7f0a4821e854cff86ec946c438458a02024-12-03T04:22:48ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-12-011110.3389/fnut.2024.14782091478209Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional studyChunlei Li0Chunlei Li1Xiangyou Pan2Shilin Xu3Jianguang Hu4Xiaoshi Zhong5Luona Wen6Jingxian Qiu7Rongshao Tan8Rongshao Tan9Department of Clinical Nutrition, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaGuangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaDepartment of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaDepartment of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaDepartment of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaDepartment of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaGuangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaGuangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaDepartment of Clinical Nutrition, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaGuangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, ChinaObjectiveWe aimed to identify the association between Health-related quality of life (HRQoL) and muscle strength in patients undergoing maintenance hemodialysis (MHD).MethodsIn this cross-sectional study from March 2021 to December 2021, 110 MHD patients with a mean age of 63.9 ± 13.0 years and a median dialysis vintage of 25.5 (12.0–52.3) months, were enrolled at a hemodialysis center in Guangzhou city, China. HRQoL was assessed using the Short Form 36 Health Survey (SF-36) and converted into the Physical Component Summary (PCS) and the Mental Component Summary (MCS). The groups were assigned according to the mean score of PCS and MCS, and those with higher PCS/MCS scores (high-PCS/MCS) were compared with those with lower PCS/MCS scores (low-PCS/MCS). Independent factors were evaluated using multivariate analysis. Muscle strength was estimated by handgrip strength (HGS).ResultsThe mean HGS was 23.7 ± 9.60 kg in men and 14.3 ± 5.30 kg in women. Compared to the high-PCS group, the low-PCS group had older age, higher levels of creatinine, total cholesterol, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6), and had lower HGS (all p < 0.05). After adjusting for confounding factors in different models, the five-model multivariate binary logistic regression analyses revealed that HGS was the only independent factor in PCS domain, but not in MCS.ConclusionHGS may be an independent factor of poor HRQoL in MHD patients, particularly in relation to physical health. The management of muscle strength may improve the HRQoL in MHD patients.Clinical trial registrationThe study was registered at https://www.chictr.org.cn/ as ChiCTR2100053790.https://www.frontiersin.org/articles/10.3389/fnut.2024.1478209/fullmuscle strengthquality of lifephysical healthsarcopeniamaintenance hemodialysis |
| spellingShingle | Chunlei Li Chunlei Li Xiangyou Pan Shilin Xu Jianguang Hu Xiaoshi Zhong Luona Wen Jingxian Qiu Rongshao Tan Rongshao Tan Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study Frontiers in Nutrition muscle strength quality of life physical health sarcopenia maintenance hemodialysis |
| title | Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study |
| title_full | Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study |
| title_fullStr | Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study |
| title_full_unstemmed | Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study |
| title_short | Handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis: a cross-sectional study |
| title_sort | handgrip strength is independently associated with physical quality of life in patients undergoing maintenance hemodialysis a cross sectional study |
| topic | muscle strength quality of life physical health sarcopenia maintenance hemodialysis |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2024.1478209/full |
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