Vaccinology in sub-Saharan Africa

We undertook a landscape analysis of vaccinology research and training in sub-Saharan Africa in order to identify key gaps and opportunities for capacity development in the field . We conducted interviews with regional and global immunisation experts, reviewed university and research centre websites...

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Main Authors: Helen Rees, Jennifer Moïsi, Shabir Ahmed Madhi
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/4/5/e001363.full
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author Helen Rees
Jennifer Moïsi
Shabir Ahmed Madhi
author_facet Helen Rees
Jennifer Moïsi
Shabir Ahmed Madhi
author_sort Helen Rees
collection DOAJ
description We undertook a landscape analysis of vaccinology research and training in sub-Saharan Africa in order to identify key gaps and opportunities for capacity development in the field . We conducted interviews with regional and global immunisation experts, reviewed university and research centre websites, searched the scientific literature and analysed donor databases as part of our mapping exercise. We found that (1) few vaccinology training programmes are available in the region; (2) vaccinology research sites are numerous but unevenly distributed across countries and subregions and of widely varying capacity; (3) donor funding favours HIV, tuberculosis and malaria vaccine development over other high-burden diseases; (4) lack of vaccine design, manufacturing and regulatory capacity slows the progress of new vaccines through the research and development pipeline and (5) vaccine implementation research garners limited support. Regional efforts to strengthen African vaccinology expertise should develop advanced vaccinology training programmes, support clinical trial and implementation research sites in geographic areas with limited capacity and conduct multidisciplinary research to help design, license and roll out new vaccines.
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spelling doaj-art-d7d6f51e553d438b84bf65a2b4cc94d02024-12-12T21:10:10ZengBMJ Publishing GroupBMJ Global Health2059-79082019-10-014510.1136/bmjgh-2018-001363Vaccinology in sub-Saharan AfricaHelen Rees0Jennifer Moïsi1Shabir Ahmed Madhi2Wits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South AfricaIndependent Consultant, Paris, FranceDepartment of Science and Technology/National Research Foundation: South African Research Chair Initiative: Vaccine Preventable Diseases—Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, Johannesburg, Gauteng, South AfricaWe undertook a landscape analysis of vaccinology research and training in sub-Saharan Africa in order to identify key gaps and opportunities for capacity development in the field . We conducted interviews with regional and global immunisation experts, reviewed university and research centre websites, searched the scientific literature and analysed donor databases as part of our mapping exercise. We found that (1) few vaccinology training programmes are available in the region; (2) vaccinology research sites are numerous but unevenly distributed across countries and subregions and of widely varying capacity; (3) donor funding favours HIV, tuberculosis and malaria vaccine development over other high-burden diseases; (4) lack of vaccine design, manufacturing and regulatory capacity slows the progress of new vaccines through the research and development pipeline and (5) vaccine implementation research garners limited support. Regional efforts to strengthen African vaccinology expertise should develop advanced vaccinology training programmes, support clinical trial and implementation research sites in geographic areas with limited capacity and conduct multidisciplinary research to help design, license and roll out new vaccines.https://gh.bmj.com/content/4/5/e001363.full
spellingShingle Helen Rees
Jennifer Moïsi
Shabir Ahmed Madhi
Vaccinology in sub-Saharan Africa
BMJ Global Health
title Vaccinology in sub-Saharan Africa
title_full Vaccinology in sub-Saharan Africa
title_fullStr Vaccinology in sub-Saharan Africa
title_full_unstemmed Vaccinology in sub-Saharan Africa
title_short Vaccinology in sub-Saharan Africa
title_sort vaccinology in sub saharan africa
url https://gh.bmj.com/content/4/5/e001363.full
work_keys_str_mv AT helenrees vaccinologyinsubsaharanafrica
AT jennifermoisi vaccinologyinsubsaharanafrica
AT shabirahmedmadhi vaccinologyinsubsaharanafrica