GSTA1/CTNNB1 axis facilitates sorafenib resistance via suppressing ferroptosis in hepatocellular carcinoma

GSTA1/CTNNB1 axis facilitates sorafenib resistance via suppressing ferroptosis in hepatocellular carcinoma

The emergence of sorafenib resistance has become a predominant impediment and formidable dilemma in the therapeutic approach for hepatocellular carcinoma (HCC). Although the approval of next-generation drugs as alternatives to sorafenib is a significant development, the concurrent use of inhibitors...

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Bibliographic Details
Main Authors: Shiwen Ma, Fei Xie, Xiaohu Wen, Yao Mawulikplimi Adzavon, Ruping Zhao, Jinyi Zhao, Han Li, Yanqi Li, Jingtao Liu, Chen Liu, Yang Yi, Pengxiang Zhao, Boqing Wang, Wei Zhao, Xuemei Ma
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Pharmacological Research
Subjects:
GSTA1
Sorafenib
Drug resistance
Ferroptosis
Hepatocellular carcinoma (HCC)
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824004353
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