Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review

Objectives To review the metrics and findings of studies evaluating effects of drug decriminalisation or legal regulation on drug availability, use or related health and social harms globally.Design Systematic review with narrative synthesis.Data sources We searched MEDLINE, Embase, PsycINFO, Web of...

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Main Authors: Ayden I Scheim, Dan Werb, Nazlee Maghsoudi, Zack Marshall, Siobhan Churchill, Carolyn Ziegler
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/9/e035148.full
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author Ayden I Scheim
Dan Werb
Nazlee Maghsoudi
Zack Marshall
Siobhan Churchill
Carolyn Ziegler
author_facet Ayden I Scheim
Dan Werb
Nazlee Maghsoudi
Zack Marshall
Siobhan Churchill
Carolyn Ziegler
author_sort Ayden I Scheim
collection DOAJ
description Objectives To review the metrics and findings of studies evaluating effects of drug decriminalisation or legal regulation on drug availability, use or related health and social harms globally.Design Systematic review with narrative synthesis.Data sources We searched MEDLINE, Embase, PsycINFO, Web of Science and six additional databases for publications from 1 January 1970 through 4 October 2018.Inclusion criteria Peer-reviewed articles or published abstracts in any language with quantitative data on drug availability, use or related health and social harms collected before and after implementation of de jure drug decriminalisation or legal regulation.Data extraction and synthesis Two independent reviewers screened titles, abstracts and articles for inclusion. Extraction and quality appraisal (modified Downs and Black checklist) were performed by one reviewer and checked by a second, with discrepancies resolved by a third. We coded study-level outcome measures into metric groupings and categorised the estimated direction of association between the legal change and outcomes of interest.Results We screened 4860 titles and 221 full-texts and included 114 articles. Most (n=104, 91.2%) were from the USA, evaluated cannabis reform (n=109, 95.6%) and focussed on legal regulation (n=96, 84.2%). 224 study outcome measures were categorised into 32 metrics, most commonly prevalence (39.5% of studies), frequency (14.0%) or perceived harmfulness (10.5%) of use of the decriminalised or regulated drug; or use of tobacco, alcohol or other drugs (12.3%). Across all substance use metrics, legal reform was most often not associated with changes in use.Conclusions Studies evaluating drug decriminalisation and legal regulation are concentrated in the USA and on cannabis legalisation. Despite the range of outcomes potentially impacted by drug law reform, extant research is narrowly focussed, with a particular emphasis on the prevalence of use. Metrics in drug law reform evaluations require improved alignment with relevant health and social outcomes.
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spelling doaj-art-d7b81bde06564c9b90a754d8d0bf3ebc2025-01-08T10:00:11ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2019-035148Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic reviewAyden I Scheim0Dan Werb1Nazlee Maghsoudi2Zack Marshall3Siobhan Churchill4Carolyn Ziegler5Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania, USADepartment of Medicine, University of California San Diego, La Jolla, California, USACentre on Drug Policy Evaluation, St Michael`s Hospital, Toronto, Ontario, CanadaDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, CanadaEpidemiology and Biostatistics, Western University, London, Ontario, Canada3 Library Services, Unity Health Toronto, Toronto, Ontario, CanadaObjectives To review the metrics and findings of studies evaluating effects of drug decriminalisation or legal regulation on drug availability, use or related health and social harms globally.Design Systematic review with narrative synthesis.Data sources We searched MEDLINE, Embase, PsycINFO, Web of Science and six additional databases for publications from 1 January 1970 through 4 October 2018.Inclusion criteria Peer-reviewed articles or published abstracts in any language with quantitative data on drug availability, use or related health and social harms collected before and after implementation of de jure drug decriminalisation or legal regulation.Data extraction and synthesis Two independent reviewers screened titles, abstracts and articles for inclusion. Extraction and quality appraisal (modified Downs and Black checklist) were performed by one reviewer and checked by a second, with discrepancies resolved by a third. We coded study-level outcome measures into metric groupings and categorised the estimated direction of association between the legal change and outcomes of interest.Results We screened 4860 titles and 221 full-texts and included 114 articles. Most (n=104, 91.2%) were from the USA, evaluated cannabis reform (n=109, 95.6%) and focussed on legal regulation (n=96, 84.2%). 224 study outcome measures were categorised into 32 metrics, most commonly prevalence (39.5% of studies), frequency (14.0%) or perceived harmfulness (10.5%) of use of the decriminalised or regulated drug; or use of tobacco, alcohol or other drugs (12.3%). Across all substance use metrics, legal reform was most often not associated with changes in use.Conclusions Studies evaluating drug decriminalisation and legal regulation are concentrated in the USA and on cannabis legalisation. Despite the range of outcomes potentially impacted by drug law reform, extant research is narrowly focussed, with a particular emphasis on the prevalence of use. Metrics in drug law reform evaluations require improved alignment with relevant health and social outcomes.https://bmjopen.bmj.com/content/10/9/e035148.full
spellingShingle Ayden I Scheim
Dan Werb
Nazlee Maghsoudi
Zack Marshall
Siobhan Churchill
Carolyn Ziegler
Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
BMJ Open
title Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
title_full Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
title_fullStr Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
title_full_unstemmed Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
title_short Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review
title_sort impact evaluations of drug decriminalisation and legal regulation on drug use health and social harms a systematic review
url https://bmjopen.bmj.com/content/10/9/e035148.full
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