Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons

Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons

Olfactory sensory neurons within the nasal epithelium detect volatile odorants and relay odor information to the central nervous system. Unlike other sensory inputs, olfactory sensory neurons interface with the external environment and project their axons directly into the central nervous system. Th...

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Main Authors: Benjamin D. W. Belfort, Johnathan D. Jia, Alexandra R. Garza, Anthony M. Insalaco, J. P. McGinnis, Brandon T. Pekarek, Joshua Ortiz-Guzman, Burak Tepe, Hu Chen, aSCENT-PD Investigators, Zhandong Liu, Benjamin R. Arenkiel, Benjamin Arenkiel, Brit Mollenhauer, Josef Penninger, Maxime Rousseaux, Armen Saghatelyan, Natalina Salmaso, Christine Stadelmann, Michael G. Schlossmacher, Julianna J. Tomlinson, John M. Woulfe, Ying Wang, Zihong Chen, Mira Jeong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
Subjects:
AAV
snRNAseq
gene therapy
olfaction
olfactory sensory neurons
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1531122/full
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https://www.frontiersin.org/articles/10.3389/fnins.2025.1531122/full

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