The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma

The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma

Summary: Most cancers re-activate telomerase to maintain telomere length and thus acquire immortality. Activating telomerase promoter mutations are found in many cancers, including melanoma. However, it is unclear when and if telomerase is strictly required during tumorigenesis. We combined the telo...

Full description

Saved in:
Bibliographic Details
Main Authors: Bruno Lopes-Bastos, Joana Nabais, Tânia Ferreira, Giulia Allavena, Mounir El Maï, Malia Bird, Seniye Targen, Lorenzo Tattini, Da Kang, Jia-Xing Yue, Gianni Liti, Tânia G. Carvalho, Miguel Godinho Ferreira
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472401386X
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items