Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties
Abstract Extracts of medicinal seeds can be used to synthesize nanoparticles (NPs) in more environmentally friendly ways than physical or chemical ways. For the first time, aqueous extract from unexploited grape seeds was used in this study to create Se/ZnO NPS utilizing a green technique, and their...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-01-01
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| Series: | AMB Express |
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| Online Access: | https://doi.org/10.1186/s13568-024-01808-y |
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| author | Samy Selim Amna A. Saddiq Ruba Abdulrahman Ashy Afra Mohammed Baghdadi Ashwag Jaman Alzahrani Ehab M. Mostafa Soad K. Al Jaouni Mohammed Yagoub Mohammed Elamir Mohamed A. Amin Ahmed M. Salah Nashwa Hagagy |
| author_facet | Samy Selim Amna A. Saddiq Ruba Abdulrahman Ashy Afra Mohammed Baghdadi Ashwag Jaman Alzahrani Ehab M. Mostafa Soad K. Al Jaouni Mohammed Yagoub Mohammed Elamir Mohamed A. Amin Ahmed M. Salah Nashwa Hagagy |
| author_sort | Samy Selim |
| collection | DOAJ |
| description | Abstract Extracts of medicinal seeds can be used to synthesize nanoparticles (NPs) in more environmentally friendly ways than physical or chemical ways. For the first time, aqueous extract from unexploited grape seeds was used in this study to create Se/ZnO NPS utilizing a green technique, and their antimicrobial activity, cytotoxicity, antioxidant activities, and plant bio stimulant properties of the economic Vicia faba L. plant were evaluated. Se/ZnO NPS is characterized by SEM and TEM images, FTIR, and XRD. Through the well diffusion assay and the scavenging of 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical experiment, biogenic Se/ZnO NPs demonstrated their antibacterial and antioxidant activities. The nanomaterial compound showed the highest inhibitory effects of 99.7, 55.63, 16.91, 10.25, 6.61, 3.83, 3.00, and 2.59%, respectively, against the cervical carcinoma (SKOV3 cells) cell line at conc of 7.81, 15.62, 31.25, 62.5, 125, 250, 500, and 1000 µg/ml, respectively, with IC50 values at 20.31 µg, resulting in 50% cell death. This study demonstrated the value of bimetallic nano-fertilizers Se/Zn in promoting faba bean development, yield features, and metabolite contents (protein, phenol, carbs, and pigments). These fertilizers are probably also advantageous for other crops. When applied in contrast to the control, 100 ppm of biological nano-Se/ZnO may generally result in the best growth and yield of faba beans. Further research is needed on the ecological aspect of biological nanofertilizers in addition to the economic one. |
| format | Article |
| id | doaj-art-d796c4d4ccdc48dcb26d9da8d498167f |
| institution | Kabale University |
| issn | 2191-0855 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | AMB Express |
| spelling | doaj-art-d796c4d4ccdc48dcb26d9da8d498167f2025-01-05T12:47:29ZengSpringerOpenAMB Express2191-08552025-01-0115111110.1186/s13568-024-01808-yBimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant propertiesSamy Selim0Amna A. Saddiq1Ruba Abdulrahman Ashy2Afra Mohammed Baghdadi3Ashwag Jaman Alzahrani4Ehab M. Mostafa5Soad K. Al Jaouni6Mohammed Yagoub Mohammed Elamir7Mohamed A. Amin8Ahmed M. Salah9Nashwa Hagagy10Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf UniversityDepartment of Biological Sciences, College of Science, University of JeddahDepartment of Biological Sciences, College of Science, University of JeddahDepartment of Biological Sciences, College of Science, University of JeddahDepartment of Biological Sciences, College of Science, University of JeddahDepartment of Pharmacognosy, College of Pharmacy, Jouf UniversityDepartment of Hematology/Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz UniversityDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf UniversityBotany and Microbiology Department, Faculty of Science, Al-Azhar UniversityThe Regional Center for Mycology and Biotechnology, Al-Azhar UniversityDepartment of Biology, College of Science & Arts at Khulis, University of JeddahAbstract Extracts of medicinal seeds can be used to synthesize nanoparticles (NPs) in more environmentally friendly ways than physical or chemical ways. For the first time, aqueous extract from unexploited grape seeds was used in this study to create Se/ZnO NPS utilizing a green technique, and their antimicrobial activity, cytotoxicity, antioxidant activities, and plant bio stimulant properties of the economic Vicia faba L. plant were evaluated. Se/ZnO NPS is characterized by SEM and TEM images, FTIR, and XRD. Through the well diffusion assay and the scavenging of 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical experiment, biogenic Se/ZnO NPs demonstrated their antibacterial and antioxidant activities. The nanomaterial compound showed the highest inhibitory effects of 99.7, 55.63, 16.91, 10.25, 6.61, 3.83, 3.00, and 2.59%, respectively, against the cervical carcinoma (SKOV3 cells) cell line at conc of 7.81, 15.62, 31.25, 62.5, 125, 250, 500, and 1000 µg/ml, respectively, with IC50 values at 20.31 µg, resulting in 50% cell death. This study demonstrated the value of bimetallic nano-fertilizers Se/Zn in promoting faba bean development, yield features, and metabolite contents (protein, phenol, carbs, and pigments). These fertilizers are probably also advantageous for other crops. When applied in contrast to the control, 100 ppm of biological nano-Se/ZnO may generally result in the best growth and yield of faba beans. Further research is needed on the ecological aspect of biological nanofertilizers in addition to the economic one.https://doi.org/10.1186/s13568-024-01808-yGrape seedsCervical carcinomaMultidrug resistance bacteriaVicia faba |
| spellingShingle | Samy Selim Amna A. Saddiq Ruba Abdulrahman Ashy Afra Mohammed Baghdadi Ashwag Jaman Alzahrani Ehab M. Mostafa Soad K. Al Jaouni Mohammed Yagoub Mohammed Elamir Mohamed A. Amin Ahmed M. Salah Nashwa Hagagy Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties AMB Express Grape seeds Cervical carcinoma Multidrug resistance bacteria Vicia faba |
| title | Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties |
| title_full | Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties |
| title_fullStr | Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties |
| title_full_unstemmed | Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties |
| title_short | Bimetallic selenium/zinc oxide nanoparticles: biological activity and plant biostimulant properties |
| title_sort | bimetallic selenium zinc oxide nanoparticles biological activity and plant biostimulant properties |
| topic | Grape seeds Cervical carcinoma Multidrug resistance bacteria Vicia faba |
| url | https://doi.org/10.1186/s13568-024-01808-y |
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