Potential effects of adenosine triphosphate and melatonin on oxidative and inflammatory optic nerve damage in rats caused by 5-fluorouracil

Potential effects of adenosine triphosphate and melatonin on oxidative and inflammatory optic nerve damage in rats caused by 5-fluorouracil

AIM: To investigate the effects of adenosine triphosphate (ATP) and melatonin, which have antioxidant and anti-inflammatory activities, on potential 5-fluorouracil (5-FU)-induced optic nerve damage in rats. METHODS: Twenty-four rats were categorized into four groups of six rats: healthy (HG), 5-FU (...

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Bibliographic Details
Main Authors: Ahmet Mehmet Somuncu, Busra Parlak Somuncu, Ahmet Duhan Ozbay, Ibrahim Cicek, Bahadir Suleyman, Renad Mammadov, Seval Bulut, Tugba Bal Tastan, Taha Abdulkadir Coban, Halis Suleyman, Aliyev Aydin
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-02-01
Series:International Journal of Ophthalmology
Subjects:
adenosine triphosphate
melatonin
5-fluorouracil
optic nerve damage
antioxidant
anti-inflammatory
Online Access:http://ies.ijo.cn/en_publish/2025/2/20250204.pdf
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