Zi Shen Wan Fang repaired blood–brain barrier integrity in diabetic cognitive impairment mice via preventing cerebrovascular cells senescence

Zi Shen Wan Fang repaired blood–brain barrier integrity in diabetic cognitive impairment mice via preventing cerebrovascular cells senescence

Abstract Background Blood–brain barrier (BBB) integrity disruption is a key pathological link of diabetes-induced cognitive impairment (DCI), but the detailed mechanism of how the diabetic environment induces BBB integrity disruption is not fully understood. Our previous study found that Zi Shen Wan...

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Bibliographic Details
Main Authors: Qingsheng Yin, Genhui Yang, Runtao Su, Jie Bu, Ying Li, Han Zhang, Yanjun Zhang, Pengwei Zhuang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Chinese Medicine
Subjects:
Diabetic cognitive impairment
Zi Shen Wan Fang
Blood–brain-barrier
Vascular senescence
Mangiferin
Online Access:https://doi.org/10.1186/s13020-024-01041-6
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