Global stability and sensitivity analysis of vector-host dengue mathematical model

Dengue impacts 129 nations, threatens over 50% of the global population, and results in around 400 million illnesses annually. The purpose of this paper was to build the global stability and sensitivity analysis of a vector-host dengue mathematical model with compartments of symptomatic and hospital...

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Main Authors: Turki D. Alharbi, Md Rifat Hasan
Format: Article
Language:English
Published: AIMS Press 2024-11-01
Series:AIMS Mathematics
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Online Access:https://www.aimspress.com/article/doi/10.3934/math.20241569?viewType=HTML
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author Turki D. Alharbi
Md Rifat Hasan
author_facet Turki D. Alharbi
Md Rifat Hasan
author_sort Turki D. Alharbi
collection DOAJ
description Dengue impacts 129 nations, threatens over 50% of the global population, and results in around 400 million illnesses annually. The purpose of this paper was to build the global stability and sensitivity analysis of a vector-host dengue mathematical model with compartments of symptomatic and hospitalized infected humans. Additionally, it aimed to assess the impact of the immunological response of vulnerable individuals, through the ingestion of natural foods, on the transmission of the disease. The solution's positivity and boundedness proved the model's mathematical well-posedness. To examine endemicity, the reproduction number was calculated using the next-generation technique. The Lyapunov function approach was employed to illustrate the model's global stability. Our mathematical discoveries were illustrated through numerical simulations of the dengue epidemic. The dynamical system sensitivity analysis suggests that the best way to control illness is to increase the immune system rate of susceptible hosts by consuming natural foods.
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issn 2473-6988
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spelling doaj-art-d766f3210ffe4c068bcb6dd88948923a2024-12-03T01:12:51ZengAIMS PressAIMS Mathematics2473-69882024-11-01911327973281810.3934/math.20241569Global stability and sensitivity analysis of vector-host dengue mathematical modelTurki D. Alharbi 0Md Rifat Hasan11. Department of Mathematics, Al-Leith University College, Umm Al-Qura University, Mecca 24231, Saudi Arabia2. Department of Applied Mathematics, Faculty of Science, Noakhali Science and Technology University, Noakhali 3814, BangladeshDengue impacts 129 nations, threatens over 50% of the global population, and results in around 400 million illnesses annually. The purpose of this paper was to build the global stability and sensitivity analysis of a vector-host dengue mathematical model with compartments of symptomatic and hospitalized infected humans. Additionally, it aimed to assess the impact of the immunological response of vulnerable individuals, through the ingestion of natural foods, on the transmission of the disease. The solution's positivity and boundedness proved the model's mathematical well-posedness. To examine endemicity, the reproduction number was calculated using the next-generation technique. The Lyapunov function approach was employed to illustrate the model's global stability. Our mathematical discoveries were illustrated through numerical simulations of the dengue epidemic. The dynamical system sensitivity analysis suggests that the best way to control illness is to increase the immune system rate of susceptible hosts by consuming natural foods.https://www.aimspress.com/article/doi/10.3934/math.20241569?viewType=HTMLbasic reproduction number (r0)denguelyapunovsensitivityglobal stability
spellingShingle Turki D. Alharbi
Md Rifat Hasan
Global stability and sensitivity analysis of vector-host dengue mathematical model
AIMS Mathematics
basic reproduction number (r0)
dengue
lyapunov
sensitivity
global stability
title Global stability and sensitivity analysis of vector-host dengue mathematical model
title_full Global stability and sensitivity analysis of vector-host dengue mathematical model
title_fullStr Global stability and sensitivity analysis of vector-host dengue mathematical model
title_full_unstemmed Global stability and sensitivity analysis of vector-host dengue mathematical model
title_short Global stability and sensitivity analysis of vector-host dengue mathematical model
title_sort global stability and sensitivity analysis of vector host dengue mathematical model
topic basic reproduction number (r0)
dengue
lyapunov
sensitivity
global stability
url https://www.aimspress.com/article/doi/10.3934/math.20241569?viewType=HTML
work_keys_str_mv AT turkidalharbi globalstabilityandsensitivityanalysisofvectorhostdenguemathematicalmodel
AT mdrifathasan globalstabilityandsensitivityanalysisofvectorhostdenguemathematicalmodel