Synthesis, characterization, and biological evaluation of coumarin-nitric oxide donor hybrids as anti-tubercular agents

Synthesis, characterization, and biological evaluation of coumarin-nitric oxide donor hybrids as anti-tubercular agents

This study presents a series of coumarin nitric oxide donor hybrids that were synthesized, and characterized using FT-IR, H NMR, C NMR, and HR-MS techniques. Initial screening for anti-tubercular activity was conducted against Mycolicibacterium smegmatis MC2155 (M.smeg) under both nutrient-rich and...

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Bibliographic Details
Main Authors:	Afeez I. Kareem, Sarel F. Malan, Erika Kapp, Sean Shamido, Jacques Joubert
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	European Journal of Medicinal Chemistry Reports
Subjects:	Mycolicibacterium smegmatis Mycobacterium tuberculosis Coumarin Nitric oxide donor Hybrids Nutrient-rich
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772417424000839
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