Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after injury. However, whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions, su...

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Bibliographic Details
Main Authors: Yan Li, Peng Hao, Hongmei Duan, Fei Hao, Wen Zhao, Yudan Gao, Zhaoyang Yang, Kwok-Fai So, Xiaoguang Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-10-01
Series:Neural Regeneration Research
Subjects:
adult endogenous neurogenesis
basic fibroblast growth factor-hyaluronic acid collagen gel
cortical remodeling
functional recovery
migration
motor cortex injury
neural circuits
neural stem cells
newborn neurons
proliferation
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01706
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https://journals.lww.com/10.4103/NRR.NRR-D-23-01706

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