Changes in the levels of immunological markers after treatment in patients with allergic rhinitis
Introduction: Monitoring changes in the levels of immune markers is of great significance in evaluating the effectiveness of treatment in patients with allergic rhinitis. Objectives: Determine the change in the concentration of immune markers after treatment in patients with allergic rhinitis ca...
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| Format: | Article |
| Language: | Spanish |
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ECIMED
2023-08-01
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| Series: | Revista Cubana de Medicina Militar |
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| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/3127 |
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| _version_ | 1841546467507961856 |
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| author | Nam Thanh Quan Thuan Duc Nghiem Thuc Minh Vu Huong Lan Do Cuong Anh Nguyen |
| author_facet | Nam Thanh Quan Thuan Duc Nghiem Thuc Minh Vu Huong Lan Do Cuong Anh Nguyen |
| author_sort | Nam Thanh Quan |
| collection | DOAJ |
| description | Introduction: Monitoring changes in the levels of immune markers is of great significance in evaluating the effectiveness of treatment in patients with allergic rhinitis.
Objectives: Determine the change in the concentration of immune markers after treatment in patients with allergic rhinitis caused by cotton dust.
Methods : A descriptive, single-group, comparative before and after intervention study on 52 patients with allergic rhinitis caused by cotton dust. Comparison of immunological markers results before and after 36 months of treatment.
Results: Total IgE concentration after treatment decreased, the median decreased from 1227.756 U/mL to 676.805 UI/mL. Serum levels of IgG, IgG4, and IgG1 in patients after treatment increased compared to before (p< 0.001). The cytokines also changed in the direction of no longer responding toward allergy. Median IL-17 decreased from 1.752 mg/dL to 0.417 mg/dL.
Conclusion: In patients with allergic rhinitis after specific sublingual desensitization treatment, IgE levels and cytokines such as IL-6 and IL-17 are significantly reduced and IgG, IgG4 and IgG1 levels are increased after treatment. |
| format | Article |
| id | doaj-art-d7290ff5e86442518a5214b483105c4a |
| institution | Kabale University |
| issn | 1561-3046 |
| language | Spanish |
| publishDate | 2023-08-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj-art-d7290ff5e86442518a5214b483105c4a2025-01-10T19:02:43ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-08-01523847Changes in the levels of immunological markers after treatment in patients with allergic rhinitisNam Thanh Quan0https://orcid.org/0000-0003-4468-4902Thuan Duc Nghiem1https://orcid.org/0000-0001-8831-7579Thuc Minh Vu2https://orcid.org/0009-0004-5221-2432Huong Lan Do3https://orcid.org/0000-0002-1019-0800Cuong Anh Nguyen4https://orcid.org/0009-0009-1472-6682Vietnam Military Medical UniversityVietnam Military Medical UniversityNational Otorhinolaryngology Hospital of VietnamVietnam Military Medical UniversityVietnam Military Medical University Introduction: Monitoring changes in the levels of immune markers is of great significance in evaluating the effectiveness of treatment in patients with allergic rhinitis. Objectives: Determine the change in the concentration of immune markers after treatment in patients with allergic rhinitis caused by cotton dust. Methods : A descriptive, single-group, comparative before and after intervention study on 52 patients with allergic rhinitis caused by cotton dust. Comparison of immunological markers results before and after 36 months of treatment. Results: Total IgE concentration after treatment decreased, the median decreased from 1227.756 U/mL to 676.805 UI/mL. Serum levels of IgG, IgG4, and IgG1 in patients after treatment increased compared to before (p< 0.001). The cytokines also changed in the direction of no longer responding toward allergy. Median IL-17 decreased from 1.752 mg/dL to 0.417 mg/dL. Conclusion: In patients with allergic rhinitis after specific sublingual desensitization treatment, IgE levels and cytokines such as IL-6 and IL-17 are significantly reduced and IgG, IgG4 and IgG1 levels are increased after treatment. https://revmedmilitar.sld.cu/index.php/mil/article/view/3127allergic rhinitiscotton dustIgEIgGcytokines. |
| spellingShingle | Nam Thanh Quan Thuan Duc Nghiem Thuc Minh Vu Huong Lan Do Cuong Anh Nguyen Changes in the levels of immunological markers after treatment in patients with allergic rhinitis Revista Cubana de Medicina Militar allergic rhinitis cotton dust IgE IgG cytokines. |
| title | Changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| title_full | Changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| title_fullStr | Changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| title_full_unstemmed | Changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| title_short | Changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| title_sort | changes in the levels of immunological markers after treatment in patients with allergic rhinitis |
| topic | allergic rhinitis cotton dust IgE IgG cytokines. |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/3127 |
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