Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic

Echinococcosis is a parasitic invasion caused by a cestode of the genus Echinococcus. Kyrgyzstan is a country in Central Asia known for an extremely high incidence of echinococcosis. A total of 10 093 subjects were screened in the Osh, Naryn and Batken regions of Kyrgyzstan in 2015–2017 by ultrasoun...

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Main Authors: Kursanbek M. Raimkulov, Vera S. Toigombaeva, Omurbek T. Kuttubaev, Zhyldyz S. Smailbekova, Asel D. Adambekova, Maria N. Ruzina, Lyudmila V. Akhmadishina, Alexander N. Lukashev
Format: Article
Language:English
Published: Cambridge University Press
Series:Parasitology
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Online Access:https://www.cambridge.org/core/product/identifier/S0031182024000763/type/journal_article
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author Kursanbek M. Raimkulov
Vera S. Toigombaeva
Omurbek T. Kuttubaev
Zhyldyz S. Smailbekova
Asel D. Adambekova
Maria N. Ruzina
Lyudmila V. Akhmadishina
Alexander N. Lukashev
author_facet Kursanbek M. Raimkulov
Vera S. Toigombaeva
Omurbek T. Kuttubaev
Zhyldyz S. Smailbekova
Asel D. Adambekova
Maria N. Ruzina
Lyudmila V. Akhmadishina
Alexander N. Lukashev
author_sort Kursanbek M. Raimkulov
collection DOAJ
description Echinococcosis is a parasitic invasion caused by a cestode of the genus Echinococcus. Kyrgyzstan is a country in Central Asia known for an extremely high incidence of echinococcosis. A total of 10 093 subjects were screened in the Osh, Naryn and Batken regions of Kyrgyzstan in 2015–2017 by ultrasound and questioned for potential risk factors. Cystic echinococcosis (CE) prevalence (combined newly diagnosed and post-surgery cases) ranged between 0.2 and 25.2% across the study regions. Typical factors, such as dog or livestock ownership, weakly affected CE risk (odds ratio [OR] = 1.18–1.83). Use of water from a well and owning a cat had a greater effect on CE risk (OR = 2.02–2.28). The risk factors of CE were highly dissimilar among the study regions, with patterns not always compatible with classical biohelminthosis transmission routes (no risk from livestock in certain areas, significant risk from using well water, owning cats). Therefore, the CE epidemic in Kyrgyzstan is not holistic in terms of potential mechanisms and risk factors, and certain areas can greatly benefit from preventive measures that will have limited efficiency elsewhere.
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institution Kabale University
issn 0031-1820
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publisher Cambridge University Press
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spelling doaj-art-d68afd1f98a1458393fca001567241842024-12-03T05:25:22ZengCambridge University PressParasitology0031-18201469-81611810.1017/S0031182024000763Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz RepublicKursanbek M. Raimkulov0https://orcid.org/0000-0002-9832-2248Vera S. Toigombaeva1Omurbek T. Kuttubaev2Zhyldyz S. Smailbekova3Asel D. Adambekova4Maria N. Ruzina5Lyudmila V. Akhmadishina6Alexander N. Lukashev7Kyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Kyrgyz RepublicKyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Kyrgyz RepublicKyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Kyrgyz RepublicKyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Kyrgyz RepublicKyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Kyrgyz RepublicMartsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, RussiaMartsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, RussiaMartsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, RussiaEchinococcosis is a parasitic invasion caused by a cestode of the genus Echinococcus. Kyrgyzstan is a country in Central Asia known for an extremely high incidence of echinococcosis. A total of 10 093 subjects were screened in the Osh, Naryn and Batken regions of Kyrgyzstan in 2015–2017 by ultrasound and questioned for potential risk factors. Cystic echinococcosis (CE) prevalence (combined newly diagnosed and post-surgery cases) ranged between 0.2 and 25.2% across the study regions. Typical factors, such as dog or livestock ownership, weakly affected CE risk (odds ratio [OR] = 1.18–1.83). Use of water from a well and owning a cat had a greater effect on CE risk (OR = 2.02–2.28). The risk factors of CE were highly dissimilar among the study regions, with patterns not always compatible with classical biohelminthosis transmission routes (no risk from livestock in certain areas, significant risk from using well water, owning cats). Therefore, the CE epidemic in Kyrgyzstan is not holistic in terms of potential mechanisms and risk factors, and certain areas can greatly benefit from preventive measures that will have limited efficiency elsewhere.https://www.cambridge.org/core/product/identifier/S0031182024000763/type/journal_articlecystic echinococcosisEchinococcusendemicprevalencerisk factorstransmission
spellingShingle Kursanbek M. Raimkulov
Vera S. Toigombaeva
Omurbek T. Kuttubaev
Zhyldyz S. Smailbekova
Asel D. Adambekova
Maria N. Ruzina
Lyudmila V. Akhmadishina
Alexander N. Lukashev
Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
Parasitology
cystic echinococcosis
Echinococcus
endemic
prevalence
risk factors
transmission
title Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
title_full Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
title_fullStr Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
title_full_unstemmed Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
title_short Dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of Kyrgyz Republic
title_sort dissimilar local risk factors among patients diagnosed with cystic echinococcosis upon voluntary screening in highly endemic regions of kyrgyz republic
topic cystic echinococcosis
Echinococcus
endemic
prevalence
risk factors
transmission
url https://www.cambridge.org/core/product/identifier/S0031182024000763/type/journal_article
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