Noninvasive Monitoring of mRFP1- and mCherry-Labeled Oncolytic Adenoviruses in an Orthotopic Breast Cancer Model by Spectral Imaging
Genetic capsid labeling of conditionally replicative adenoviruses (CRAds) with fluorescent tags offers a potentially more accurate monitoring of those virotherapy agents in vivo. The capsid of an infectivity-enhanced CRAd, Ad5/3, delta 24, was genetically labeled with monomeric red fluorescent prote...
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Main Authors: | Anton V. Borovjagin, Lacey R. McNally, Minghui Wang, David T. Curiel, Mary J. MacDougall, Kurt R. Zinn |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-03-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00003 |
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