Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study
The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5–11 yr) entered the study: 11 were...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2018/4843985 |
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| author | Giovanni Buccino Anna Molinaro Claudia Ambrosi Daniele Arisi Lorella Mascaro Chiara Pinardi Andrea Rossi Roberto Gasparotti Elisa Fazzi Jessica Galli |
| author_facet | Giovanni Buccino Anna Molinaro Claudia Ambrosi Daniele Arisi Lorella Mascaro Chiara Pinardi Andrea Rossi Roberto Gasparotti Elisa Fazzi Jessica Galli |
| author_sort | Giovanni Buccino |
| collection | DOAJ |
| description | The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5–11 yr) entered the study: 11 were treated children, and 7 served as controls. Outcome measures were scores on two functional scales: Melbourne Assessment of Unilateral Upper Limb Function Scale (MUUL) and the Assisting Hand Assessment (AHA). We collected functional scores before treatment (T1), at the end of treatment (T2), and at two months of follow-up (T3). As compared to controls, treated children improved significantly in both scales at T2 and this improvement persisted at T3. AOT has therefore the potential to become a routine rehabilitation practice in children with CP. Twelve out of 18 enrolled children also underwent a functional magnetic resonance study at T1 and T2. As compared to controls, at T2, treated children showed stronger activation in a parieto-premotor circuit for hand-object interactions. These findings support the notion that AOT contributes to reorganize brain circuits subserving the impaired function rather than activating supplementary or vicariating ones. |
| format | Article |
| id | doaj-art-d67c403867f7452dbb4e7c475bb6fbf2 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-d67c403867f7452dbb4e7c475bb6fbf22025-02-03T05:47:45ZengWileyNeural Plasticity2090-59041687-54432018-01-01201810.1155/2018/48439854843985Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging StudyGiovanni Buccino0Anna Molinaro1Claudia Ambrosi2Daniele Arisi3Lorella Mascaro4Chiara Pinardi5Andrea Rossi6Roberto Gasparotti7Elisa Fazzi8Jessica Galli9Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, ItalyUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, ItalyDepartment of Diagnostic Imaging, Neuroradiology Unit, University of Brescia, Brescia, ItalyDepartment of Paediatrics, Ospedale di Cremona, Cremona, ItalyDepartment of Diagnostic Imaging, Medical Physics Unit, ASST Spedali Civili, Brescia, ItalyNeuroscience Unit, Department of Medicine and Surgery, University of Parma, Parma, ItalyUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, ItalyDepartment of Diagnostic Imaging, Neuroradiology Unit, University of Brescia, Brescia, ItalyUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, ItalyUnit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, ItalyThe aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5–11 yr) entered the study: 11 were treated children, and 7 served as controls. Outcome measures were scores on two functional scales: Melbourne Assessment of Unilateral Upper Limb Function Scale (MUUL) and the Assisting Hand Assessment (AHA). We collected functional scores before treatment (T1), at the end of treatment (T2), and at two months of follow-up (T3). As compared to controls, treated children improved significantly in both scales at T2 and this improvement persisted at T3. AOT has therefore the potential to become a routine rehabilitation practice in children with CP. Twelve out of 18 enrolled children also underwent a functional magnetic resonance study at T1 and T2. As compared to controls, at T2, treated children showed stronger activation in a parieto-premotor circuit for hand-object interactions. These findings support the notion that AOT contributes to reorganize brain circuits subserving the impaired function rather than activating supplementary or vicariating ones.http://dx.doi.org/10.1155/2018/4843985 |
| spellingShingle | Giovanni Buccino Anna Molinaro Claudia Ambrosi Daniele Arisi Lorella Mascaro Chiara Pinardi Andrea Rossi Roberto Gasparotti Elisa Fazzi Jessica Galli Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study Neural Plasticity |
| title | Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study |
| title_full | Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study |
| title_fullStr | Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study |
| title_full_unstemmed | Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study |
| title_short | Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study |
| title_sort | action observation treatment improves upper limb motor functions in children with cerebral palsy a combined clinical and brain imaging study |
| url | http://dx.doi.org/10.1155/2018/4843985 |
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