Research progress of endoplasmic reticulum stress in peritoneal dialysis

Peritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found...

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Main Authors: Li Yan-ling, Zou Xun-liang
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2025-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010
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author Li Yan-ling
Zou Xun-liang
author_facet Li Yan-ling
Zou Xun-liang
author_sort Li Yan-ling
collection DOAJ
description Peritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found that endoplasmic reticulum (ER) stress is closely related to peritoneal dialysis-associated complications. This article summarized the research progress of ER stress in peritoneal dialysis at home and abroad in recent years, mainly from the aspects of cell death, inflammatory signal transduction and epithelial-mesenchymal transition induced by ER stress through three classic signaling pathways, aiming to provide new ideas and directions for the prevention and treatment of peritoneal dialysis-related peritonitis and peritoneal fibrosis.
format Article
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institution Kabale University
issn 1671-2390
language zho
publishDate 2025-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-d6595b8c8bc445419c868edd4f9c07ed2025-01-17T08:29:52ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902025-01-01251697310.3969/j.issn.1671-2390.2025.01.0101671-2390(2025)01-0069-05Research progress of endoplasmic reticulum stress in peritoneal dialysisLi Yan-ling0Zou Xun-liang1Department of Nephrology,the Fifth Affiliated Hospital of Zunyi Medical University,Zhuhai 519000,ChinaDepartment of Nephrology,the Fifth Affiliated Hospital of Zunyi Medical University,Zhuhai 519000,ChinaPeritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found that endoplasmic reticulum (ER) stress is closely related to peritoneal dialysis-associated complications. This article summarized the research progress of ER stress in peritoneal dialysis at home and abroad in recent years, mainly from the aspects of cell death, inflammatory signal transduction and epithelial-mesenchymal transition induced by ER stress through three classic signaling pathways, aiming to provide new ideas and directions for the prevention and treatment of peritoneal dialysis-related peritonitis and peritoneal fibrosis.http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010endoplasmic reticulum stressperitoneal dialysisperitoneal dialysis-associated peritonitisperitoneal fibrosis
spellingShingle Li Yan-ling
Zou Xun-liang
Research progress of endoplasmic reticulum stress in peritoneal dialysis
Linchuang shenzangbing zazhi
endoplasmic reticulum stress
peritoneal dialysis
peritoneal dialysis-associated peritonitis
peritoneal fibrosis
title Research progress of endoplasmic reticulum stress in peritoneal dialysis
title_full Research progress of endoplasmic reticulum stress in peritoneal dialysis
title_fullStr Research progress of endoplasmic reticulum stress in peritoneal dialysis
title_full_unstemmed Research progress of endoplasmic reticulum stress in peritoneal dialysis
title_short Research progress of endoplasmic reticulum stress in peritoneal dialysis
title_sort research progress of endoplasmic reticulum stress in peritoneal dialysis
topic endoplasmic reticulum stress
peritoneal dialysis
peritoneal dialysis-associated peritonitis
peritoneal fibrosis
url http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010
work_keys_str_mv AT liyanling researchprogressofendoplasmicreticulumstressinperitonealdialysis
AT zouxunliang researchprogressofendoplasmicreticulumstressinperitonealdialysis