Research progress of endoplasmic reticulum stress in peritoneal dialysis
Peritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found...
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Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2025-01-01
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Series: | Linchuang shenzangbing zazhi |
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Online Access: | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010 |
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author | Li Yan-ling Zou Xun-liang |
author_facet | Li Yan-ling Zou Xun-liang |
author_sort | Li Yan-ling |
collection | DOAJ |
description | Peritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found that endoplasmic reticulum (ER) stress is closely related to peritoneal dialysis-associated complications. This article summarized the research progress of ER stress in peritoneal dialysis at home and abroad in recent years, mainly from the aspects of cell death, inflammatory signal transduction and epithelial-mesenchymal transition induced by ER stress through three classic signaling pathways, aiming to provide new ideas and directions for the prevention and treatment of peritoneal dialysis-related peritonitis and peritoneal fibrosis. |
format | Article |
id | doaj-art-d6595b8c8bc445419c868edd4f9c07ed |
institution | Kabale University |
issn | 1671-2390 |
language | zho |
publishDate | 2025-01-01 |
publisher | Editorial Department of Journal of Clinical Nephrology |
record_format | Article |
series | Linchuang shenzangbing zazhi |
spelling | doaj-art-d6595b8c8bc445419c868edd4f9c07ed2025-01-17T08:29:52ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902025-01-01251697310.3969/j.issn.1671-2390.2025.01.0101671-2390(2025)01-0069-05Research progress of endoplasmic reticulum stress in peritoneal dialysisLi Yan-ling0Zou Xun-liang1Department of Nephrology,the Fifth Affiliated Hospital of Zunyi Medical University,Zhuhai 519000,ChinaDepartment of Nephrology,the Fifth Affiliated Hospital of Zunyi Medical University,Zhuhai 519000,ChinaPeritoneal dialysis is an effective renal replacement therapy for the treatment of end-stage renal disease. Prolonged peritoneal dialysis is prone to peritoneal inflammation, neoangiogenesis, and fibrosis, ultimately leading to interruption of peritoneal dialysis treatment. Recent studies have found that endoplasmic reticulum (ER) stress is closely related to peritoneal dialysis-associated complications. This article summarized the research progress of ER stress in peritoneal dialysis at home and abroad in recent years, mainly from the aspects of cell death, inflammatory signal transduction and epithelial-mesenchymal transition induced by ER stress through three classic signaling pathways, aiming to provide new ideas and directions for the prevention and treatment of peritoneal dialysis-related peritonitis and peritoneal fibrosis.http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010endoplasmic reticulum stressperitoneal dialysisperitoneal dialysis-associated peritonitisperitoneal fibrosis |
spellingShingle | Li Yan-ling Zou Xun-liang Research progress of endoplasmic reticulum stress in peritoneal dialysis Linchuang shenzangbing zazhi endoplasmic reticulum stress peritoneal dialysis peritoneal dialysis-associated peritonitis peritoneal fibrosis |
title | Research progress of endoplasmic reticulum stress in peritoneal dialysis |
title_full | Research progress of endoplasmic reticulum stress in peritoneal dialysis |
title_fullStr | Research progress of endoplasmic reticulum stress in peritoneal dialysis |
title_full_unstemmed | Research progress of endoplasmic reticulum stress in peritoneal dialysis |
title_short | Research progress of endoplasmic reticulum stress in peritoneal dialysis |
title_sort | research progress of endoplasmic reticulum stress in peritoneal dialysis |
topic | endoplasmic reticulum stress peritoneal dialysis peritoneal dialysis-associated peritonitis peritoneal fibrosis |
url | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.010 |
work_keys_str_mv | AT liyanling researchprogressofendoplasmicreticulumstressinperitonealdialysis AT zouxunliang researchprogressofendoplasmicreticulumstressinperitonealdialysis |