Therapeutic Effects of GLP-1 Receptor Agonists and DPP-4 Inhibitors in Neuropathic Pain: Mechanisms and Clinical Implications

Therapeutic Effects of GLP-1 Receptor Agonists and DPP-4 Inhibitors in Neuropathic Pain: Mechanisms and Clinical Implications

Glucagon-like peptide-1 (GLP-1) is a peptide hormone secreted by the small intestine upon food intake. GLP-1 enhances insulin secretion, suppresses glucagon release, and promotes satiety, resulting in reduced food consumption and subsequent weight loss. Endogenous GLP-1 has a very short half-life an...

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Bibliographic Details
Main Authors: Yaswanth Kuthati, Venkata Naga Goutham Davuluri, Chih-Shung Wong
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
Subjects:
glucagon-like peptide-1
dipeptidyl-peptidase-IV inhibitors
neuropathic pain
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2218-273X/15/5/622
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