Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae

Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae

Abstract Background Haemophilus influenzae is an opportunistic bacterial pathogen that can cause severe respiratory tract and invasive infections. The emergence of β-lactamase-negative ampicillin-resistant (BLNAR) strains and unclear correlations between genotypic (i.e., gBLNAR) and phenotypic resis...

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Main Authors: Margo Diricks, Sabine Petersen, Lennart Bartels, Thiên-Trí Lâm, Heike Claus, Maria Paula Bajanca-Lavado, Susanne Hauswaldt, Ricardo Stolze, Omar Jiménez Vázquez, Christian Utpatel, Stefan Niemann, Jan Rupp, Inken Wohlers, Matthias Merker
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Genome Medicine
Subjects:
Haemophilus influenzae
Ampicillin resistance
Cefotaxime resistance
BLNAR
MIC
Genome-wide association study
Online Access:https://doi.org/10.1186/s13073-024-01406-4
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