CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development
The CLAVATA pathway plays a key role in the regulation of multicellular shoot and root meristems in flowering plants. In Arabidopsis, CLAVATA 3-like signaling peptides (CLEs) act via receptor-like kinases CLAVATA 1 and CRINKLY 4 (CR4). In the moss Physcomitrium patens, PpCLAVATA and PpCR4 were previ...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Plant Signaling & Behavior |
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| Online Access: | http://dx.doi.org/10.1080/15592324.2024.2386502 |
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| _version_ | 1846095052183437312 |
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| author | Alain Shumbusho C. Jill Harrison Viktor Demko |
| author_facet | Alain Shumbusho C. Jill Harrison Viktor Demko |
| author_sort | Alain Shumbusho |
| collection | DOAJ |
| description | The CLAVATA pathway plays a key role in the regulation of multicellular shoot and root meristems in flowering plants. In Arabidopsis, CLAVATA 3-like signaling peptides (CLEs) act via receptor-like kinases CLAVATA 1 and CRINKLY 4 (CR4). In the moss Physcomitrium patens, PpCLAVATA and PpCR4 were previously studied independently and shown to play conserved roles in the regulation of cell proliferation and differentiation. The plant calpain DEFECTIVE KERNEL 1 (DEK1) has been identified as another key regulator of cell division and cell fate in vascular plants and bryophytes. The functional interaction between CLAVATA, CR4, and DEK1 remains unknown. Here, we show that P. patens crinkly4 and dek1 mutants respond differently to CLE peptide treatments suggesting their distinct roles in the CLAVATA pathway. Reduced CLAVATA-mediated suppression of leafy shoot growth in Δcr4 mutants indicates that PpCR4 is involved in CLV3p perception, most likely as a receptor. The CLV3p strongly suppressed leaf vein development in Δcr4 mutants, suggesting that other receptors are involved in these processes and indicating a potential role of PpCR4 in organ sensitization to CLEs. |
| format | Article |
| id | doaj-art-d60c4c2a255240749aed6f9fc4200e82 |
| institution | Kabale University |
| issn | 1559-2316 1559-2324 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Plant Signaling & Behavior |
| spelling | doaj-art-d60c4c2a255240749aed6f9fc4200e822025-01-02T11:44:27ZengTaylor & Francis GroupPlant Signaling & Behavior1559-23161559-23242024-12-0119110.1080/15592324.2024.23865022386502CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore developmentAlain Shumbusho0C. Jill Harrison1Viktor Demko2Comenius University in BratislavaUniversity of BristolComenius University in BratislavaThe CLAVATA pathway plays a key role in the regulation of multicellular shoot and root meristems in flowering plants. In Arabidopsis, CLAVATA 3-like signaling peptides (CLEs) act via receptor-like kinases CLAVATA 1 and CRINKLY 4 (CR4). In the moss Physcomitrium patens, PpCLAVATA and PpCR4 were previously studied independently and shown to play conserved roles in the regulation of cell proliferation and differentiation. The plant calpain DEFECTIVE KERNEL 1 (DEK1) has been identified as another key regulator of cell division and cell fate in vascular plants and bryophytes. The functional interaction between CLAVATA, CR4, and DEK1 remains unknown. Here, we show that P. patens crinkly4 and dek1 mutants respond differently to CLE peptide treatments suggesting their distinct roles in the CLAVATA pathway. Reduced CLAVATA-mediated suppression of leafy shoot growth in Δcr4 mutants indicates that PpCR4 is involved in CLV3p perception, most likely as a receptor. The CLV3p strongly suppressed leaf vein development in Δcr4 mutants, suggesting that other receptors are involved in these processes and indicating a potential role of PpCR4 in organ sensitization to CLEs.http://dx.doi.org/10.1080/15592324.2024.2386502cell-to-cell signalingclavataleaf developmentphyscomitrium patenscrinkly4 kinasedefective kernel |
| spellingShingle | Alain Shumbusho C. Jill Harrison Viktor Demko CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development Plant Signaling & Behavior cell-to-cell signaling clavata leaf development physcomitrium patens crinkly4 kinase defective kernel |
| title | CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development |
| title_full | CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development |
| title_fullStr | CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development |
| title_full_unstemmed | CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development |
| title_short | CLE peptides act via the receptor-like kinase CRINKLY 4 in Physcomitrium patens gametophore development |
| title_sort | cle peptides act via the receptor like kinase crinkly 4 in physcomitrium patens gametophore development |
| topic | cell-to-cell signaling clavata leaf development physcomitrium patens crinkly4 kinase defective kernel |
| url | http://dx.doi.org/10.1080/15592324.2024.2386502 |
| work_keys_str_mv | AT alainshumbusho clepeptidesactviathereceptorlikekinasecrinkly4inphyscomitriumpatensgametophoredevelopment AT cjillharrison clepeptidesactviathereceptorlikekinasecrinkly4inphyscomitriumpatensgametophoredevelopment AT viktordemko clepeptidesactviathereceptorlikekinasecrinkly4inphyscomitriumpatensgametophoredevelopment |