Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis
BackgroundMarital status is among the factors influencing type 2 diabetes mellitus (T2DM). However, the precise relationship remains incompletely understood. This meta-analysis aims to evaluate the association between marital status and the incidence of T2DM.MethodsA review and meta-analysis of obse...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1485490/full |
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| author | Mohammad Amin Karimi Sara Binaei Seyed Hadi Hashemi Pegah Refahi Ensiyeh Olama Elnaz Olama Aydin Mohammadpour Reza Mostafaei Yonjali Mohadeseh Poudineh Niloofar Deravi |
| author_facet | Mohammad Amin Karimi Sara Binaei Seyed Hadi Hashemi Pegah Refahi Ensiyeh Olama Elnaz Olama Aydin Mohammadpour Reza Mostafaei Yonjali Mohadeseh Poudineh Niloofar Deravi |
| author_sort | Mohammad Amin Karimi |
| collection | DOAJ |
| description | BackgroundMarital status is among the factors influencing type 2 diabetes mellitus (T2DM). However, the precise relationship remains incompletely understood. This meta-analysis aims to evaluate the association between marital status and the incidence of T2DM.MethodsA review and meta-analysis of observational studies were conducted to investigate the relationship between marital status and diabetes incidence. We searched three databases, including PubMed, Google Scholar, and Scopus, for relevant studies published up to August 16th, 2023. In our initial search, we identified a total of 358 articles. After a demanding screening process involving evaluating titles, abstracts, and full-text content, we ultimately included six studies for our meta-analysis.ResultComprising a total of 1,440,904 participants, our study found that in comparison to married individuals, unmarried participants exhibited a higher likelihood of developing diabetes [odds ratio (OR): 1.47, 95% confidence interval (CI): 0.88–2.45, I2: 91%, p-value = 0.14]. Divorced participants had a reduced likelihood of developing diabetes compared to married participants (OR: 0.84, 95% CI: 0.77–0.91, I2: 17%, p < 0.001). Similarly, widowed participants showed a lower risk of developing diabetes compared to divorced participants (OR: 0.35, 95% CI: 0.26–0.46, I2: 83%, p < 0.00001).ConclusionThis study provides strong evidence of links between marital status and type 2 diabetes risk. Unmarried individuals are more susceptible to T2DM, divorced individuals have a lower risk, and widowed individuals exhibit reduced T2DM risk. Further research should investigate underlying mechanisms and confounding factors. |
| format | Article |
| id | doaj-art-d5ed5a889c6842c987884f830e082da5 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-d5ed5a889c6842c987884f830e082da52025-01-03T06:46:44ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.14854901485490Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysisMohammad Amin Karimi0Sara Binaei1Seyed Hadi Hashemi2Pegah Refahi3Ensiyeh Olama4Elnaz Olama5Aydin Mohammadpour6Reza Mostafaei Yonjali7Mohadeseh Poudineh8Niloofar Deravi9School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranEndocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, IranStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranFaculty of Medicine, Georgian National University SEU, Tbilisi, GeorgiaFaculty of Medicine, Georgian National University SEU, Tbilisi, GeorgiaStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, School of Medicine, Zanjan University of Medical Sciences, Zanjan, IranStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranBackgroundMarital status is among the factors influencing type 2 diabetes mellitus (T2DM). However, the precise relationship remains incompletely understood. This meta-analysis aims to evaluate the association between marital status and the incidence of T2DM.MethodsA review and meta-analysis of observational studies were conducted to investigate the relationship between marital status and diabetes incidence. We searched three databases, including PubMed, Google Scholar, and Scopus, for relevant studies published up to August 16th, 2023. In our initial search, we identified a total of 358 articles. After a demanding screening process involving evaluating titles, abstracts, and full-text content, we ultimately included six studies for our meta-analysis.ResultComprising a total of 1,440,904 participants, our study found that in comparison to married individuals, unmarried participants exhibited a higher likelihood of developing diabetes [odds ratio (OR): 1.47, 95% confidence interval (CI): 0.88–2.45, I2: 91%, p-value = 0.14]. Divorced participants had a reduced likelihood of developing diabetes compared to married participants (OR: 0.84, 95% CI: 0.77–0.91, I2: 17%, p < 0.001). Similarly, widowed participants showed a lower risk of developing diabetes compared to divorced participants (OR: 0.35, 95% CI: 0.26–0.46, I2: 83%, p < 0.00001).ConclusionThis study provides strong evidence of links between marital status and type 2 diabetes risk. Unmarried individuals are more susceptible to T2DM, divorced individuals have a lower risk, and widowed individuals exhibit reduced T2DM risk. Further research should investigate underlying mechanisms and confounding factors.https://www.frontiersin.org/articles/10.3389/fmed.2024.1485490/fulldiabetesdivorcedmarriedrelationshipsinglewidow |
| spellingShingle | Mohammad Amin Karimi Sara Binaei Seyed Hadi Hashemi Pegah Refahi Ensiyeh Olama Elnaz Olama Aydin Mohammadpour Reza Mostafaei Yonjali Mohadeseh Poudineh Niloofar Deravi Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis Frontiers in Medicine diabetes divorced married relationship single widow |
| title | Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis |
| title_full | Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis |
| title_fullStr | Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis |
| title_full_unstemmed | Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis |
| title_short | Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis |
| title_sort | marital status and risk of type 2 diabetes among middle aged and elderly population a systematic review and meta analysis |
| topic | diabetes divorced married relationship single widow |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1485490/full |
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