GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer

GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer

Abstract Background Advanced prostate cancer (PCa) often initially responds to androgen receptor signaling inhibitors (ARSI) but frequently develops resistance, driven by tumor heterogeneity and therapeutic pressure. Addressing the clinical challenge of identifying non-responsive patients and discov...

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Main Authors: Chuanfan Zhong, Jiaxing Wang, Hangyang Peng, Jianming Lu, Zining Long, Zhuoyuan Lin, Guo Chen, Chao Cai, Shilong Cheng, Zhongjie Chen, Le Zhang, Weibo Zhong, Rujun Mo, Xiangming Mao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
GG-NER
Prostate cancer
ARSI
ACTL6A
Enzalutamide
Online Access:https://doi.org/10.1186/s12964-024-01977-0
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