Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial study protocol

Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial study protocol

Abstract Background Some evidence suggests that fluid resuscitation with lactated Ringer’s solution (LR) may have an anti-inflammatory effect on acute pancreatitis (AP) when compared to normal saline (NS) and may be associated with a decrease in severity, but existing single-center randomized contro...

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Main Authors: Lucía Guilabert, Karina Cárdenas-Jaén, Alicia Vaillo-Rocamora, Ana García García de Paredes, Ankit Chhoda, Sunil G. Sheth, Carlos López-Valero, Pedro Zapater, Eva M. Navarrete-Muñoz, Patrick Maisonneuve, Yasmin G. Hernández-Barco, Gabriele Capurso, James L. Buxbaum, Enrique de-Madaria, for the ERICA consortium
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Trials
Subjects:
Acute pancreatitis
Fluid resuscitation
Lactated Ringer solution
Normal saline
Randomized controlled trial
Online Access:https://doi.org/10.1186/s13063-024-08539-2
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https://doi.org/10.1186/s13063-024-08539-2

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