FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy
Conclusion: FTO could act as a protective effector during hepatic IRI, associated with decreased apoptosis and autophagy. FTO-mediated m6A demethylation modification may be an important therapeutic target for hepatic IRI.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/grp/5587859 |
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| _version_ | 1841542631983677440 |
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| author | Pi-Xiao Wang Ling Zhu Mei Xiang Rixin Zhang Xiaolin Zheng Zhi Zheng Kai Li |
| author_facet | Pi-Xiao Wang Ling Zhu Mei Xiang Rixin Zhang Xiaolin Zheng Zhi Zheng Kai Li |
| author_sort | Pi-Xiao Wang |
| collection | DOAJ |
| description | Conclusion: FTO could act as a protective effector during hepatic IRI, associated with decreased apoptosis and autophagy. FTO-mediated m6A demethylation modification may be an important therapeutic target for hepatic IRI. |
| format | Article |
| id | doaj-art-d5c1c910b8c34c55842dc83491627df9 |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-d5c1c910b8c34c55842dc83491627df92025-01-14T00:00:04ZengWileyGastroenterology Research and Practice1687-630X2025-01-01202510.1155/grp/5587859FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and AutophagyPi-Xiao Wang0Ling Zhu1Mei Xiang2Rixin Zhang3Xiaolin Zheng4Zhi Zheng5Kai Li6Department of Hepatobiliary and Pancreatic SurgeryDepartment of Hepatobiliary and Pancreatic SurgeryDepartment of CardiologyDepartment of Hepatobiliary and Pancreatic SurgeryDepartment of Hepatobiliary and Pancreatic SurgeryDepartment of Hepatobiliary and Pancreatic SurgeryDepartment of Hepatobiliary and Pancreatic SurgeryConclusion: FTO could act as a protective effector during hepatic IRI, associated with decreased apoptosis and autophagy. FTO-mediated m6A demethylation modification may be an important therapeutic target for hepatic IRI.http://dx.doi.org/10.1155/grp/5587859 |
| spellingShingle | Pi-Xiao Wang Ling Zhu Mei Xiang Rixin Zhang Xiaolin Zheng Zhi Zheng Kai Li FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy Gastroenterology Research and Practice |
| title | FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy |
| title_full | FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy |
| title_fullStr | FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy |
| title_full_unstemmed | FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy |
| title_short | FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy |
| title_sort | fto alleviates hepatic ischemia reperfusion injury by regulating apoptosis and autophagy |
| url | http://dx.doi.org/10.1155/grp/5587859 |
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