A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa
The quantification and electrochemical behavior of methyldopa in tablet and urine samples were carried out using a glassy carbon electrode modified with double-charged ionic liquid and a layered double hydroxide. Magnesium aluminum layered double hydroxides/double charged diazabicyclo [2.2.2] octane...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Iranian Chemical Society
2024-01-01
|
| Series: | Nanochemistry Research |
| Subjects: | |
| Online Access: | http://www.nanochemres.org/article_184827_c6cf9d094bcf72668b128acfa89b2eeb.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841545156618092544 |
|---|---|
| author | Mir Mahdi Abolghasemi Marzieh Piryaei Elnaz Tartibi |
| author_facet | Mir Mahdi Abolghasemi Marzieh Piryaei Elnaz Tartibi |
| author_sort | Mir Mahdi Abolghasemi |
| collection | DOAJ |
| description | The quantification and electrochemical behavior of methyldopa in tablet and urine samples were carried out using a glassy carbon electrode modified with double-charged ionic liquid and a layered double hydroxide. Magnesium aluminum layered double hydroxides/double charged diazabicyclo [2.2.2] octane ionic liquid (Mg/Al LDH/DABCO-IL) was prepared and immobilized on a glassy carbon electrode. The results of Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) demonstrated that Mg/Al LDH/DABCO-IL was successfully synthesized. The cyclic voltammogram of methyldopa on the modified electrode exhibited a well-defined anodic peak at 0.63 V in 0.1 M of ammonia buffer. The experimental parameters were optimized and the kinetic parameters were investigated. Under the optimized conditions, the fabricated modified electrode exhibited excellent performance in the linear range of 0.23-860 μM with a correlation coefficient of 0.9959. The detection limit was 0.076 μM (S/N = 3). The fabricated electrode showed good reproducibility, stability, and selectivity properties. The method was successfully applied for the determination of methyldopa in pharmaceutical and urine samples. |
| format | Article |
| id | doaj-art-d59c578eaa7b4e659ef1b1aede5df494 |
| institution | Kabale University |
| issn | 2538-4279 2423-818X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Iranian Chemical Society |
| record_format | Article |
| series | Nanochemistry Research |
| spelling | doaj-art-d59c578eaa7b4e659ef1b1aede5df4942025-01-12T10:25:02ZengIranian Chemical SocietyNanochemistry Research2538-42792423-818X2024-01-019191810.22036/NCR.2024.01.02184827A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of MethyldopaMir Mahdi Abolghasemi0Marzieh Piryaei1Elnaz Tartibi2Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranDepartment of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranDepartment of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranThe quantification and electrochemical behavior of methyldopa in tablet and urine samples were carried out using a glassy carbon electrode modified with double-charged ionic liquid and a layered double hydroxide. Magnesium aluminum layered double hydroxides/double charged diazabicyclo [2.2.2] octane ionic liquid (Mg/Al LDH/DABCO-IL) was prepared and immobilized on a glassy carbon electrode. The results of Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) demonstrated that Mg/Al LDH/DABCO-IL was successfully synthesized. The cyclic voltammogram of methyldopa on the modified electrode exhibited a well-defined anodic peak at 0.63 V in 0.1 M of ammonia buffer. The experimental parameters were optimized and the kinetic parameters were investigated. Under the optimized conditions, the fabricated modified electrode exhibited excellent performance in the linear range of 0.23-860 μM with a correlation coefficient of 0.9959. The detection limit was 0.076 μM (S/N = 3). The fabricated electrode showed good reproducibility, stability, and selectivity properties. The method was successfully applied for the determination of methyldopa in pharmaceutical and urine samples.http://www.nanochemres.org/article_184827_c6cf9d094bcf72668b128acfa89b2eeb.pdfionic liquidmodified electrodemethyldopalayered double hydroxidedouble-charged diazabicyclo |
| spellingShingle | Mir Mahdi Abolghasemi Marzieh Piryaei Elnaz Tartibi A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa Nanochemistry Research ionic liquid modified electrode methyldopa layered double hydroxide double-charged diazabicyclo |
| title | A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa |
| title_full | A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa |
| title_fullStr | A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa |
| title_full_unstemmed | A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa |
| title_short | A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa |
| title_sort | low resistance hybrid nanomaterial composed of double charged ionic liquid and a layered double hydroxide type al mg dodecyl sulfate for electrochemical determination of methyldopa |
| topic | ionic liquid modified electrode methyldopa layered double hydroxide double-charged diazabicyclo |
| url | http://www.nanochemres.org/article_184827_c6cf9d094bcf72668b128acfa89b2eeb.pdf |
| work_keys_str_mv | AT mirmahdiabolghasemi alowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa AT marziehpiryaei alowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa AT elnaztartibi alowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa AT mirmahdiabolghasemi lowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa AT marziehpiryaei lowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa AT elnaztartibi lowresistancehybridnanomaterialcomposedofdoublechargedionicliquidandalayereddoublehydroxidetypealmgdodecylsulfateforelectrochemicaldeterminationofmethyldopa |