A Low-Resistance Hybrid Nanomaterial Composed of Double-Charged Ionic Liquid and a Layered Double Hydroxide (Type Al/Mg-Dodecyl Sulfate) for Electrochemical Determination of Methyldopa
The quantification and electrochemical behavior of methyldopa in tablet and urine samples were carried out using a glassy carbon electrode modified with double-charged ionic liquid and a layered double hydroxide. Magnesium aluminum layered double hydroxides/double charged diazabicyclo [2.2.2] octane...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iranian Chemical Society
2024-01-01
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| Series: | Nanochemistry Research |
| Subjects: | |
| Online Access: | http://www.nanochemres.org/article_184827_c6cf9d094bcf72668b128acfa89b2eeb.pdf |
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| Summary: | The quantification and electrochemical behavior of methyldopa in tablet and urine samples were carried out using a glassy carbon electrode modified with double-charged ionic liquid and a layered double hydroxide. Magnesium aluminum layered double hydroxides/double charged diazabicyclo [2.2.2] octane ionic liquid (Mg/Al LDH/DABCO-IL) was prepared and immobilized on a glassy carbon electrode. The results of Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) demonstrated that Mg/Al LDH/DABCO-IL was successfully synthesized. The cyclic voltammogram of methyldopa on the modified electrode exhibited a well-defined anodic peak at 0.63 V in 0.1 M of ammonia buffer. The experimental parameters were optimized and the kinetic parameters were investigated. Under the optimized conditions, the fabricated modified electrode exhibited excellent performance in the linear range of 0.23-860 μM with a correlation coefficient of 0.9959. The detection limit was 0.076 μM (S/N = 3). The fabricated electrode showed good reproducibility, stability, and selectivity properties. The method was successfully applied for the determination of methyldopa in pharmaceutical and urine samples. |
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| ISSN: | 2538-4279 2423-818X |