Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis
ABSTRACT: Background: There are few meta-analyses examining the prognostic value of right ventricular ejection fraction (RVEF) for a specific type of cardiovascular disease (CVD). The aim of this study was to compare the association of cardiac magnetic resonance (CMR)-derived RVEF with adverse outc...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Journal of Cardiovascular Magnetic Resonance |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1097664724011451 |
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| author | Tetsuji Kitano František Bartoš Yosuke Nabeshima Alex Ali Sayour Attila Kovács Masaaki Takeuchi |
| author_facet | Tetsuji Kitano František Bartoš Yosuke Nabeshima Alex Ali Sayour Attila Kovács Masaaki Takeuchi |
| author_sort | Tetsuji Kitano |
| collection | DOAJ |
| description | ABSTRACT: Background: There are few meta-analyses examining the prognostic value of right ventricular ejection fraction (RVEF) for a specific type of cardiovascular disease (CVD). The aim of this study was to compare the association of cardiac magnetic resonance (CMR)-derived RVEF with adverse outcomes for several specific types of CVD, using a robust Bayesian model-averaged meta-analysis. Methods: Three databases were searched for CMR articles reporting hazard ratios (HRs) of RVEF restricted to a specific type of CVD. For each specific type of CVD, Bayesian model-averaged meta-analyses with and without publication bias adjustments were conducted to evaluate the strength of evidence for RVEF according to the Bayes factor (BF). Results: Among 108 articles (21,166 patients) analyzing 11 CVD types, pooled HR for 5% reduction in RVEF assessed by publication bias-unadjusted, Bayesian model-averaged meta-analysis offered moderate or strong evidence of an association with outcomes for all types of CVD (HR: 1.07–1.37, BF10: 4.3–9.6 * 107). In contrast, a robust Bayesian model-averaged meta-analysis, adjusted for publication bias, found moderate or strong evidence in favor of an association of RVEF with outcomes only in hypertrophic cardiomyopathy (HR: 1.19, 95% credible interval (CrI): 0.98–1.42, BF10: 5.0), dilated cardiomyopathy (HR: 1.16, 95% CrI: 1–1.22, BF10: 23.3), pulmonary hypertension (HR: 1.05, 95% CrI: 1–1.12, BF10: 3.0), and aortic stenosis (HR: 1.15, 95% CrI: 0.97–1.34, BF10: 4.2). There was weak evidence for an association of RVEF with adverse outcomes in seven other CVDs. Conclusion: In a Bayesian meta-analysis adjusted for publication bias, there was moderate or strong evidence for an association of RVEF with outcomes for only four CVDs. Additional data may strengthen evidence regarding other CVDs. |
| format | Article |
| id | doaj-art-d56e53eee36e47c8a576f15fdfd45e97 |
| institution | Kabale University |
| issn | 1097-6647 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Cardiovascular Magnetic Resonance |
| spelling | doaj-art-d56e53eee36e47c8a576f15fdfd45e972024-12-16T05:34:56ZengElsevierJournal of Cardiovascular Magnetic Resonance1097-66472024-01-01262101118Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysisTetsuji Kitano0František Bartoš1Yosuke Nabeshima2Alex Ali Sayour3Attila Kovács4Masaaki Takeuchi5Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan; Department of Clinical Training and Career Support Center, Mie University Hospital, Tsu, Japan; Corresponding author. Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.Department of Psychological Methods, University of Amsterdam, Amsterdam, NetherlandsDepartment of Cardiovascular Medicine, Saga University, Saga, JapanThe Heart and Vascular Center, Semmelweis University, Budapest, HungaryThe Heart and Vascular Center, Semmelweis University, Budapest, HungaryDepartment of Laboratory and Transfusion Medicine, University of Occupational and Environmental Health Hospital, Kitakyushu, JapanABSTRACT: Background: There are few meta-analyses examining the prognostic value of right ventricular ejection fraction (RVEF) for a specific type of cardiovascular disease (CVD). The aim of this study was to compare the association of cardiac magnetic resonance (CMR)-derived RVEF with adverse outcomes for several specific types of CVD, using a robust Bayesian model-averaged meta-analysis. Methods: Three databases were searched for CMR articles reporting hazard ratios (HRs) of RVEF restricted to a specific type of CVD. For each specific type of CVD, Bayesian model-averaged meta-analyses with and without publication bias adjustments were conducted to evaluate the strength of evidence for RVEF according to the Bayes factor (BF). Results: Among 108 articles (21,166 patients) analyzing 11 CVD types, pooled HR for 5% reduction in RVEF assessed by publication bias-unadjusted, Bayesian model-averaged meta-analysis offered moderate or strong evidence of an association with outcomes for all types of CVD (HR: 1.07–1.37, BF10: 4.3–9.6 * 107). In contrast, a robust Bayesian model-averaged meta-analysis, adjusted for publication bias, found moderate or strong evidence in favor of an association of RVEF with outcomes only in hypertrophic cardiomyopathy (HR: 1.19, 95% credible interval (CrI): 0.98–1.42, BF10: 5.0), dilated cardiomyopathy (HR: 1.16, 95% CrI: 1–1.22, BF10: 23.3), pulmonary hypertension (HR: 1.05, 95% CrI: 1–1.12, BF10: 3.0), and aortic stenosis (HR: 1.15, 95% CrI: 0.97–1.34, BF10: 4.2). There was weak evidence for an association of RVEF with adverse outcomes in seven other CVDs. Conclusion: In a Bayesian meta-analysis adjusted for publication bias, there was moderate or strong evidence for an association of RVEF with outcomes for only four CVDs. Additional data may strengthen evidence regarding other CVDs.http://www.sciencedirect.com/science/article/pii/S1097664724011451RVEFCardiac magnetic resonanceMeta-analysisBayesPrognostic value |
| spellingShingle | Tetsuji Kitano František Bartoš Yosuke Nabeshima Alex Ali Sayour Attila Kovács Masaaki Takeuchi Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis Journal of Cardiovascular Magnetic Resonance RVEF Cardiac magnetic resonance Meta-analysis Bayes Prognostic value |
| title | Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis |
| title_full | Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis |
| title_fullStr | Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis |
| title_full_unstemmed | Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis |
| title_short | Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis |
| title_sort | impact of cardiovascular magnetic resonance derived right ventricular ejection fraction on adverse outcomes a robust bayesian model averaged meta analysis |
| topic | RVEF Cardiac magnetic resonance Meta-analysis Bayes Prognostic value |
| url | http://www.sciencedirect.com/science/article/pii/S1097664724011451 |
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