Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance

Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance

As a metabolic center, the liver prevents inappropriate immune responses to abundant dietary antigens within the liver that could result in liver injury. This self-preservation mechanism can however decrease the efficiency of immunosurveillance of malignant cells by CD8 T cells. Hepatocellular carci...

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Bibliographic Details
Main Authors:	Kimberly N. Kremer, Hadeel A. Khammash, Anjelica M. Miranda, Lauren N. Rutt, Shannon M. Twardy, Paige E. Anton, Margaret L. Campbell, Christian Garza-Ortiz, David J. Orlicky, Roberta Pelanda, Rebecca L. McCullough, Raul M. Torres
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Immunology
Subjects:	liver sinusoidal endothelial cells T cell exhaustion hepatocellular carcinoma T cell Immunosuppression
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497788/full
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