Mutagenicity and DNA damage assessment of locally produced nano-hydroxyapatite-silica-glass ionomer cement on human periodontal ligament fibroblasts using Ames and Comet assays

Mutagenicity and DNA damage assessment of locally produced nano-hydroxyapatite-silica-glass ionomer cement on human periodontal ligament fibroblasts using Ames and Comet assays

Aim: This research assessed the mutagenicity and DNA damage of a novel type of nano-hydroxyapatite-silica glass ionomer cement (nano-HA-SiO2-GIC) and a conventional GIC (cGIC) using Ames and Comet assays. Methods: Cell viability was tested on human periodontal ligament fibroblasts (HPLFs) using 3.12...

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Bibliographic Details
Main Authors: Fayez Hussain Niazi, Norhayati Luddin, Abdurahman Niazy, Suharni Mohamad, Masitah Hayati Harun, Mohammed Noushad, Kannan Thirumulu Ponnuraj
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Saudi Dental Journal
Subjects:
Cell viability
DNA damage
Genotoxicity
Human periodontal ligament fibroblast
Mutagenicity
Nano-hydroxyapatite-silica-glass ionomer cement
Online Access:http://www.sciencedirect.com/science/article/pii/S1013905224002384
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